抗Beclin 1抗体 | Anti-Beclin 1 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-Fr analysis of rat lymph node tissue using GTX37770 Beclin 1 antibody. Dilution : 2.5μg/ml
	IHC-P analysis of rat lymph node tissue using GTX37770 Beclin 1 antibody. Dilution : 2.5μg/ml
	IHC-Fr analysis of rat pancreas tissue using GTX37770 Beclin 1 antibody. Dilution : 2.5μg/ml
	WB analysis of rat lymph node (Lane 1), mouse spinal cord (Lane 2), rat rectum (Lane 3), mouse testis (Lane 4), human breast cancer (Lane 5), rat pancreas (Lane 6) tissue lysates using GTX37770 Beclin 1 antibody. Dilution : 1μg/ml
	IHC-P analysis of human breast cancer tissue using GTX37770 Beclin 1 antibody. Dilution : 2.5μg/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, IHC-Fr
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:100-2000
IHC-P	1:100-600
IHC-Fr	Assay dependent

Not tested in other applications.

Calculated MW	52 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	10 mM PBS, 0.02% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.
Concentration	0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	KLH conjugated synthetic peptide derived from human Beclin 1.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	beclin 1 , ATG6 , VPS30 , beclin1
Cellular Localization	Cytoplasm,Endosome membrane,Endoplasmic reticulum membrane,Endosome,Nucleus
Background	This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Database	・ Gene ID: 8678 BECN1 ・ UniProt: Q14457 BECN1

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Scherr AL et al. Int J Mol Sci 2020; 21 (3) Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer Cells.	Application : IHC-P Reactivity : Human

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