抗Caspase 12抗体 | Anti-Caspase 12 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

DATA IMAGES

IHC-P analysis of rat testis tissue using GTX37762 Caspase 12 antibody.

目次に戻る

製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Rat

目次に戻る

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
IHC-P	1:400-800

Not tested in other applications.

Calculated MW	39 kDa. ( Note )

目次に戻る

PROPERTIES

Form	Liquid
Buffer	0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.
Concentration	0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	KLH conjugated synthetic peptide derived between 211-290 amino acids of human Caspase 12
Purification	Protein A purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	caspase 12 (gene/pseudogene) , CASP-12 , CASP12P1
Background	Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011]
Database	・ Gene ID: 100506742 CASP12 ・ UniProt: Q6UXS9 CASP12

目次に戻る

REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Pelissier-Rota MA et al. Int J Biochem Cell Biol 2015; 65 (Epub) : 239-56 Nicotine-induced cellular stresses and autophagy in human cancer colon cells: A supportive effect on cell homeostasis via up-regulation of Cox-2 and PGE(2) production.	Application : WB Reactivity : Human

目次に戻る