抗NIS抗体 | Anti-NIS antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of rat thyroid gland tissue using GTX37599 NIS antibody.
	IHC-P analysis of rat brain tissue using GTX37599 NIS antibody. Dilution : 1:200
	IHC-P analysis of rat thyroid gland tissue using GTX37599 NIS antibody.
	IHC-Fr analysis of human thyroid tissue using GTX37599 NIS antibody. Dilution : 1:200
	WB analysis of rat brain (Lane 1) and rat kidney (Lane 2) tissue lysates using GTX37599 NIS antibody. Dilution : 1:200

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, IHC-Fr, IHC
Reactivity	Human, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500-2000
IHC-P	1:400-800
IHC-Fr	Assay dependent
IHC	Assay dependent

Not tested in other applications.

Calculated MW	69 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.
Concentration	0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	KLH conjugated synthetic peptide derived between 535-608 amino acids of human NIS
Purification	Protein A purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	solute carrier family 5 member 5 , NIS , TDH1
Cellular Localization	Membrane; Multi-pass membrane protein
Background	This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009]
Database	・ Gene ID: 6528 SLC5A5 ・ UniProt: Q92911 SLC5A5

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Kaushik N et al. Cell Commun Signal 2019; 17 (1) : 12 Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation.
De Rose F et al. J Nucl Med 2018; (Epub) Galectin-3 targeting in thyroid orthotopic tumors opens new ways to characterize thyroid cancer.
Yildirim-Poyraz N et al. Ann Nucl Med 2013; 27 (8) : 786-90 False-positive iodine-131 whole body scan due to a benign dermal lesion; intradermal nevus ((131)I uptake in a benign nevus).	Application : IHC Reactivity : Human

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