抗c-Myc抗体 | Anti-c-Myc antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

WB analysis of 200, 100, and 50ng of E. coli lysate containing tagged fusion protein using GTX30518 c-Myc antibody.Dilution : 1:25000

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製品情報

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IP, ELISA, IHC
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:1,000-1:20,000
ICC/IF	1:100-1:400
IP	1-4μg antibody/mg lysate
ELISA	1:1,000-1:30,000 (Detection) ; 1:100-1:500 (Coating)
IHC	Assay dependent

Not tested in other applications.

Calculated MW	49 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS pH 7.2, 0.09% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Amino acids 410-419 (EQKLISEEDL) of human myc conjugated to KLH.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	MRTL,MYC,MYCC,bHLHe39,cMyc,vmyc avian myelocytomatosis viral oncogene homolog,cmyc,MYC proto-oncogene, bHLH transcription factor
Cellular Localization	Nucleus,Nucleoplasm,Nucleolus
Background	This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Database	・ Gene ID: 4609 MYC ・ UniProt: P01106 MYC

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Tien YT et al. Vet J 2015; Downregulation of the KLF4 transcription factor inhibits the proliferation and migration of canine mammary tumor cells.	Application : WB Reactivity : Human

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