抗CDKN2A / p14ARF抗体 | Anti-CDKN2A / p14ARF antibody

• 2025/10/01

  試薬 プレゼント

  [GNT]【数量限定】早いもの勝ち！ジェンタくんキーホルダープレゼントキャンペーン[～2025/10/31] 終了間近

  期間：2025/10/01 ～2025/10/31

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  GeneTex International Corporation（GNT）

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human prostate adenocarcinoma tissue using GTX30434 CDKN2A / p14ARF antibody. Dilution : 1:250
	IHC-P analysis of human prostate carcinoma tissue using GTX30434 CDKN2A / p14ARF antibody. Dilution : 1 μg/ml
	WB analysis of BT-549 (positive control), U2OS (negative control) and IMR90 overexpressing CDKN2A / p14ARF cell lysate using GTX30434 CDKN2A / p14ARF antibody.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA
Reactivity	Human, Primate

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500 - 1:2500
IHC-P	1:100 - 1:500
ELISA	1:100 - 1:2000

Not tested in other applications.

Predict Reactivity	Marmoset, Orangutan(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	Tris-Citrate/Phosphate pH 7.0 - 8.0, 0.09% Sodium Azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	The epitope recognized by this antibody maps to a region between residue 125 and the C-terminus (residue 173) of human p14ARF using the numbering given in entry NP_478102.1 (GeneID 1029).
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	cyclin dependent kinase inhibitor 2A , ARF , CDK4I , CDKN2 , CMM2 , INK4 , INK4A , MLM , MTS-1 , MTS1 , P14 , P14ARF , P16 , P16-INK4A , P16INK4 , P16INK4A , P19 , P19ARF , TP16
Cellular Localization	Cytoplasm,Nucleus,nucleoplasm,Nucleolus
Background	The INK4a-ARF locus is comprised of two tumor suppressors, p16INK4a and p14ARF. These two proteins are encoded through differential splicing of alternative first exons. The p16INK4a (exon 1alpha) protein inhibits the cyclin D-dependent kinases (CDK) that control the phosphorylation of the Rb protein and cell proliferation. The p14ARF gene product complexes with the MDM2 protein within the nucleus, thus modulating the activity of the p53 protein. P14ARF is a potent tumor suppressor in the presence of wild-type p53, while mutant p53 substantially reduces growth inhibition by p14ARF.
Database	・ Gene ID: 1029 CDKN2A ・ UniProt: P42771 ・ UniProt: Q8N726

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