抗Caspase 7 [Mch3 1-1-11]抗体 | Anti-Caspase 7 [Mch3 1-1-11] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of HeLa cell lysate using GTX30242 Caspase 7 antibody[Mch3 1-1-11].
	WB analysis of HeLa cell lysate using GTX30242 Caspase 7 antibody[Mch3 1-1-11].

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	Mch3 1-1-11
Isotype	IgG1
Application	WB
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500 - 1:1000

Not tested in other applications.

Calculated MW	34 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Ascites, 0.1% Sodium Azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Full-length recombinant human Caspase 7 [UniProt# P55210]
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	caspase 7 , CASP-7 , CMH-1 , ICE-LAP3 , LICE2 , MCH3
Cellular Localization	Cytoplasm
Background	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq]
Database	・ Gene ID: 840 CASP7 ・ UniProt: P55210 CASP7

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Blanc-Brude OP et al. Clin Cancer Res 2003; 9 (7):2683-92 Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis.

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