抗Survivin [60.11]抗体 | Anti-Survivin [60.11] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of rat aorta smooth muscle tissue lysate using GTX30241 Survivin antibody [60.11].
	WB analysis of HeLa cell lysate (30μg) using GTX30241 Survivin antibody [60.11]. Loading : 30μgDilution : 1 μg/ml
	WB analysis of mock or overexpressing Survivin cell lysate using GTX30241 Survivin antibody [60.11].
	IHC-P analysis of ovary cancer tissue using GTX30241 Survivin antibody [60.11].
	ICC/IF analysis of HeLa cells using GTX30241 Survivin antibody [60.11]. Green : primary antibodyBlue : Hoechst 33258

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	60.11
Isotype	IgG2a
Application	WB, ICC/IF, IHC-P, IHC-Fr, IP, ELISA
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	1:100
IHC-P	Assay dependent
IHC-Fr	Assay dependent
IP	1:10 - 1:500
ELISA	Assay dependent

Not tested in other applications.

Calculated MW	16 kDa. ( Note )
Specificity/Sensitivity	This antibody is specific for the cytoplasmic form of survivin.

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PROPERTIES

Form	Liquid
Buffer	Ascites diulted with PBS, 0.05% Sodium Azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Full length recombinant human Survivin [UniProt# O15392]
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	baculoviral IAP repeat containing 5 , API4 , EPR-1
Cellular Localization	Cytoplasm,Nucleus
Background	This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq]
Database	・ Gene ID: 332 BIRC5 ・ UniProt: O15392 BIRC5

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