抗Insulin抗体 | Anti-Insulin antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Insulin antibody detects Insulin protein at cytoplasm by immunohistochemical analysis.Sample: Paraffin-embedded human pancreas.Insulin stained by Insulin antibody (GTX27842) diluted at 1:50.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

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製品情報

Host	Guinea pig
Clonality	Polyclonal
Isotype	IgG
Application	ICC/IF, IHC-P, IHC-Fr
Reactivity	Human, Mouse

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APPLICATION

Application Note

For IHC/ICC: Use at a dilution of 1:50-1:100. Prolonged fixation in buffered formalin can destroy the epitope. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	12 kDa. ( Note )
Specificity/Sensitivity	This antibody stains beta (b) cells of the Langerhan's islets in human pancreas.

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PROPERTIES

Form	Liquid
Buffer	Phosphate-buffered saline, pH 7.2, containing 0.2% BSA and 0.09% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration	0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Full length human protein
Purification	Neat Serum
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Insulin , Iddm , Iddm1 , Iddm2 , Ilpr , Irdn , Mody10 , Ins
Cellular Localization	Secreted
Background	Insulin is a hormone that is synthesized, stored and secreted by beta islets of Langerhans cells of the pancreas.
Database	・ Gene ID: 3630 ・ UniProt: P01308

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Mouna El Mehdi et al. bioRxiv 2019; (Epub) Glucose homeostasis is impaired in mice deficient for the neuropeptide 26RFa (QRFP).	Application : IHC-P Reactivity : Mouse
Chien HJ et al. Am J Physiol Gastrointest Liver Physiol 2019; Human pancreatic afferent and efferent nerves: mapping and 3-D illustration of exocrine, endocrine, and adipose innervation.	Reactivity : Mouse
Tang SC et al. Diabetologia 2017; (Epub) Pancreatic neuro-insular network in young mice revealed by 3D panoramic histology.
Tang SC et al. Diabetologia 2017; (Epub) Human pancreatic neuro-insular network in health and fatty infiltration.
Yamashita-Sugahara Y et al. Sci Rep 2016; 6 : 35908 An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors.	Application : ICC/IF Reactivity : Human

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