抗CX3CR1抗体 | Anti-CX3CR1 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, IHC-Fr, FACS, IP, Neutralizing/Blocking
Reactivity	Rat

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APPLICATION

Application Note

IHC-P: Use at a dilution of 1/100 - 1/500. IHC-Fr: Use at a dilution of 1/100 - 1/500. IP: Use at a dilution of 1/300 - 1/800. Neut: Use at an assay dependent dilution. WB: Use at a dilution of 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	40 kDa. ( Note )
Specificity/Sensitivity	Recombinant and natural rat CX3CR1

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PROPERTIES

Form	Liquid
Buffer	Preservative: 0.1% Sodium Azide; Constituents: PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Rat
Immunogen	Recombinant amino terminal fragment (Rat).
Purification	Protein A purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	C-X3-C Motif Chemokine Receptor 1 , Rbs11 , Cx3Cr1
Background	Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine (ref 1). RatCX3CR1, also named RBS11, was first cloned from rat brainstem, pituitary and/or spinal cord cDNA libraries (ref 2). A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor (ref 3). The human equivalent receptor is known as V28, which has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.
Database	・ Gene ID: 171056 ・ UniProt: P35411

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Sidibe A et al. Nat Commun 2018; 9 (1) : 355 Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours.

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