抗Caspase 9 (p10)抗体 | Anti-Caspase 9 (p10) antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human, Mouse, Rat

目次に戻る

APPLICATION

Application Note

WB: Use at a dilution of 1/200. Predicted molecular weight: 46k precursor and 10k subunit. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	46 kDa. ( Note )
Specificity/Sensitivity	It could recognize mouse, rat, and human caspase-9 (p10) and caspase-9 precursor

目次に戻る

PROPERTIES

Form	Liquid
Buffer	Preservative: 0.1% Sodium Azide; Constituents: 0.2% Gelatin, PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic peptide mapping to an internal domain of human Caspase 9/p10 subunit.
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	Caspase 9 , Apaf-3 , Apaf3 , Ice-Lap6 , Mch6 , Ppp1R56 , Casp9
Background	The activation of the initiator caspase, caspase 9, is regulated by the apoptosome, which is composed of cytochrome c bound to Apaf1 and dATP. The apoptosome responds to a diverse array of apoptotic stimuli that initiate the caspase cascade that ultimately results in cell death. The cascade of events starts with the proteolytic cleavage of caspase 9, that then cleaves downstream caspases, caspase 3, 6, and 7. The apoptotic initiating activity of caspase 9 can be regulated by XIAP, X-linked inhibitor-of-apoptosis protein; through the binding of caspase 9 at its amino terminus while it is bound to the apoptosome. This inhibition of caspase 9 activity has been shown to be relieved by Smac/DIABLO through its interaction with XIAP.
Database	・ Gene ID: 842 ・ UniProt: P55211

目次に戻る