抗DR5抗体 | Anti-DR5 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of HeLa (H) and K562 (K) cell lysates using GTX24106 DR5 antibody.
	ICC/IF analysis of HeLa cells using GTX24106 DR5 antibody.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF
Reactivity	Human, Mouse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	2μg/ml
ICC/IF	5μg/ml

Not tested in other applications.

Calculated MW	48 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS pH 7.4
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Peptide corresponding to aa 388- 407 of human DR5 precursor (accession no. AF012535).
Purification	Purified by affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	CD262,DR5,KILLER,KILLER/DR5,TNF receptor superfamily member 10b,TNFRSF10B,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9,TRAIL-R2
Cellular Localization	Membrane
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Database	・ Gene ID: 8795 TNFRSF10B ・ UniProt: O14763 TNFRSF10B

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