抗Integrin beta 1 / CD29 [4B7R]抗体 | Anti-Integrin beta 1 / CD29 [4B7R] antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	4B7R
Isotype	IgG1
Application	ICC/IF, IHC-Fr, FACS
Reactivity	Human, Pig

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
ICC/IF	Assay dependent
IHC-Fr	Assay dependent
FACS	Assay dependent

Not tested in other applications.

Calculated MW	88 kDa. ( Note )

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PROPERTIES

Form	Liquid
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Antigen Species	Human
Immunogen	Human melanoma V+B2 cell line
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	integrin subunit beta 1 , CD29 , FNRB , GPIIA , MDF2 , MSK12 , VLA-BETA , VLAB
Cellular Localization	Cell membrane,Cell junction
Background	Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 3688 ITGB1 ・ UniProt: P05556 ITGB1

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Itou J et al. Biochim Biophys Acta 2016; 1864 (1) : 76-88 The Sal-like 4 - integrin α6β1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells.
Ueda S et al. J Clin Immunol 2010; 30 (6):861-71 Up-regulation of ?1 integrin on tonsillar T cells and its induction by in vitro stimulation with α-streptococci in patients with pustulosis Palmaris et Plantaris.

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