抗RPSA [MLuC5]抗体 | Anti-RPSA [MLuC5] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

IHC-P analysis of tissue using GTX23099 RPSA antibody [MLuC5].

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	MLuC5
Isotype	IgM
Application	WB, ICC/IF, IHC-P, IHC-Fr, FACS, Blocking, Inhibition assay
Reactivity	Human, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-P	Assay dependent
IHC-Fr	Assay dependent
FACS	Assay dependent
Blocking	Assay dependent
Inhibition assay	Assay dependent

Not tested in other applications.

Calculated MW	33 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Buffer, BSA and Azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Antigen Species	Human
Immunogen	Small cell lung carcinoma N592 live cells
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	ribosomal protein SA , 37LRP , 67LR , ICAS , LAMBR , LAMR1 , LBP , LBP/p40 , LRP , LRP/LR , NEM/1CHD4 , SA , lamR , p40
Cellular Localization	Cell membrane,Cytoplasm,Nucleus
Background	Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 3921 RPSA ・ UniProt: P08865 RPSA

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Piazza M et al. J Neurosurg 2017; : 43112 Simulating vasogenic brain edema using chronic VEGF infusion.	Application : IHC-Fr Reactivity : Rat
Wang ZM et al. Cell Physiol Biochem 2014; 33 (5):1349-58 Green tea polyphenol epigallocatechin-3-gallate inhibits TNF-α-induced production of monocyte chemoattractant protein-1 in human umbilical vein endothelial cells.	Application : WB, Blocking Reactivity : Human

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