抗Caspase 9 (active)抗体 | Anti-Caspase 9 (active) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

WB analysis of (1) untreated and (2) Etoposide treated Jurkat cell lysate using GTX22324 Caspase 9 (active) antibody.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IP
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.5-4 μg/ml
ICC/IF	Assay dependent
IP	10-20 μg/ml

Not tested in other applications.

Calculated MW	50 kDa. ( Note )
Specificity/Sensitivity	This antibody recognizes only the cleaved caspase 9 (37 kDa). It does not recognize full-length caspase 9 or any other caspase.

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PROPERTIES

Form	Liquid
Buffer	PBS, 50% glycerol, 0.5% BSA, 0.02% thimerosal
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic peptide mapping to the N-terminus adjacent to Asp330 of human caspase-9
Purification	Purified by affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	caspase 9 , AI115399 , APAF-3 , AW493809 , CASP-9 , Caspase-9 , ICE-LAP6 , Mch6
Background	This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]
Database	・ Gene ID: 12371 Casp9 ・ UniProt: Q8C3Q9 Casp9

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Accordi B et al. Leukemia 2013; 27 (5) : 1019-27 AMPK inhibition enhances apoptosis in MLL-rearranged pediatric B-acute lymphoblastic leukemia cells.	Application : ICC/IF Reactivity : Human

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