抗Bcl-2 (phospho Thr56)抗体 | Anti-Bcl-2 (phospho Thr56) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	Western blot analysis of extracts from MDA435 cells treated with sorbtiol (0.4M, 30min) using Bcl-2 (phospho-Thr56) antibody (GTX21908).
	Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using BCL-2 (phospho-Thr56) antibody (GTX21908).

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human

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APPLICATION

Application Note

WB: Use at a dilution of 1:500-1:1000 IHC: Use at a dilution of 1:50-1:100

Calculated MW	26 kDa. ( Note )
Specificity/Sensitivity	Human Bcl-2 phospho Thr56

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PROPERTIES

Form	Liquid
Buffer	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human BCL-2 around the phosphorylation site of threonine 56 (G-H-TP-P-H).
Purification	Affinity purified with antigen
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Bcl2, Apoptosis Regulator , Bcl-2 , Ppp1R50 , Bcl2
Cellular Localization	Endoplasmic
Background	Bcl2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of Bcl2, such as in the case of translocation of Bcl2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C terminal ends.
Database	・ Gene ID: 596 ・ UniProt: P10415

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