抗CCR5抗体 | Anti-CCR5 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

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製品情報

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, ELISA, IHC
Reactivity	Human

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APPLICATION

Application Note

For ELISA: Use at a dilution of 1:50,000. For ICC: Use at a dilution of 1:300. For IHC: Use at a dilution of 1:300. For WB: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW	41 kDa. ( Note )
Positive Control	Human peripheral blood leukocytes (ICC)
Specificity/Sensitivity	This antibody binds to CCR 5 receptors on human peripheral blood leukocytes as determined by immunocytochemistry.

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PROPERTIES

Form	Liquid
Buffer	10 mM KHPO4, 140 mM NaCl with 1 mg/ml BSA containing 0.1% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic peptide: YQVSSPIYDINYYTSEPCQKINVKQIAA (Human).
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	C-C Motif Chemokine Receptor 5 (Gene/Pseudogene) , Cc-Ckr-5 , Ccckr5 , Ccr-5 , Cd195 , Ckr-5 , Ckr5 , Cmkbr5 , Iddm22 , Ccr5
Background	Receptors for the C-C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co-receptor. The chemokine receptor CCR 5 is one of the co-receptors used by primary isolates of HIV-1. Extracellular domains of CCR 5 are important for HIV entry into the target cells.
Database	・ Gene ID: 1234 ・ UniProt: P51681

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Sugasawa H et al. Int J Cancer 2008; 122 (11) : 2535-41 Gastric cancer cells exploit CD4+ cell-derived CCL5 for their growth and prevention of CD8+ cell-involved tumor elimination.	Application : IHC Reactivity : Human
Sugasawa H et al. J Surg Oncol 2008; 97 (5) : 445-50 Prognostic significance of expression of CCL5/RANTES receptors in patients with gastric cancer.	Application : IHC Reactivity : Human

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