抗CD44 [IM7] (Biotin)抗体 | Anti-CD44 [IM7] (Biotin) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Staining of C57 splenocytes with Anti-Mouse CD44: Biotin (purple histogram) or Rat IgG2b Isotype Control: Biotin (open histogram) followed by UltraAvidin: PE

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製品情報

Host	Rat
Clonality	Monoclonal
Clone Name	IM7
Isotype	IgG2b
Application	IHC-Fr, FACS, IP
Reactivity	Human, Bovine, Cat, Dog, Pig, Horse

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APPLICATION

Application Note

FACS: Use 1μg for 10^6 cells. IHC-Fr (acetone fixed): Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	82 kDa. ( Note )
Specificity/Sensitivity	Recognizes all isoforms of the Pgp-1 cell surface glycoprotein. The CD44 is present on B-cells, monocytes, macrophages and certain subsets of thymocytes and peripheral T-cells. Mice with the Ly-24.1 allotype have high densities of CD44+ T-cells, while Ly-24.2 strains are low expressors.

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PROPERTIES

Form	Liquid
Buffer	Preservative: 0.1% Sodium Azide. Constituents: 1.0% BSA, 0.01M PBS, pH 7.2
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration	0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen	Unfortunately, this information is considered to be commercially sensitive
Purification	Protein A purified
Conjugation	Biotin
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Cd44 Molecule (Indian Blood Group) , Cdw44 , Cspg8 , Ecmr-Iii , Hcell , Hutch-I , In , Lhr , Mc56 , Mdu2 , Mdu3 , Mic4 , Pgp1 , Cd44
Cellular Localization	Type I membrane protein
Background	CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
Database	・ Gene ID: 960 ・ UniProt: P16070

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