抗OPG (Biotin)抗体 | Anti-OPG (Biotin) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	ELISA analysis of human OPG recombinant protein(0.2 - 0.4 ng/well) using GTX18068 OPG antibody (Biotin)(detection antibody) at 0.25- 1.0 ug/ml and Anti-Human OPG as a capture antibody.
	ELISA analysis of human OPG recombinant protein (0.2 – 0.4 ng/well) using GTX18068 OPG antibody (Biotin). Working concentration : 0.25- 1.0 ug/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ELISA, sELISA
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.1 - 0.2 μg/mL
ELISA	0.15 - 0.30 μg/mL
sELISA	0.25 - 1.0 ug/ml
Note : sELISA Capture : Anti-Human OPG antibody, Detection : GTX18068

Not tested in other applications.

Calculated MW	46 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS pH 7.2
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hOPG (human OPG).
Purification	Purified by affinity chromatography
Conjugation	Biotin
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	TNF receptor superfamily member 11b , OCIF , OPG , PDB5 , TR1
Cellular Localization	Secreted
Background	Osteoprotegerin (OPG) belongs to the TNF receptor (TNFR) family. Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Database	・ Gene ID: 4982 TNFRSF11B ・ UniProt: O00300 TNFRSF11B

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