抗c-Myc [8]抗体 | Anti-c-Myc [8] antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	8
Isotype	IgG2a
Application	WB, IP
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

IP: Use at an assay dependent dilution (with and without SDS). WB: Use at an assay dependent dilution. Detects bands of approximately 64 & 67 kDa (phospho myc)(predicted molecular weight: 49 kDa). Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	49 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Preservative: 0.08% Sodium Azide. Constituents: PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Recombinant full length protein (Human).
Purification	IgG fraction
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Myc Proto-Oncogene, Bhlh Transcription Factor , Mrtl , Mycc , Bhlhe39 , C-Myc , Myc
Cellular Localization	Nuclear
Background	The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Database	・ Gene ID: 4609 ・ UniProt: P01106

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