抗BAFF [Buffy-1] (FITC)抗体 | Anti-BAFF [Buffy-1] (FITC) antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Rat
Clonality	Monoclonal
Clone Name	Buffy-1
Isotype	IgG2a
Application	FACS
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
FACS	4 μg/mL
Note : FACS HEK 293T cells (5 x 10⁵) were mock transfected or transfected with BAFF.

Not tested in other applications.

Calculated MW	31 kDa. ( Note )
Specificity/Sensitivity	Recognizes membrane-bound human BAFF. Detects endogenous protein by Flow Cytometry.

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PROPERTIES

Form	Liquid
Buffer	PBS with 0.02% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	BAFF (monoclonal Buffy-1) antibody was raised against recombinant human soluble BAFF (aa. 83-285).
Purification	Purified IgG2a
Conjugation	Fluorescein isothiocyanate (FITC)
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	TNF superfamily member 13b , BAFF , BLYS , CD257 , DTL , TALL-1 , TALL1 , THANK , TNFSF20 , TNLG7A , ZTNF4
Cellular Localization	Cell membrane; Single-pass type II membrane protein
Background	Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL1 (for TNF- and ApoL- related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NFkB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNFa and TRAIL,THANK was shown to activate NF-kB and c-jun N terminal kinase (JNK) and to induce apoptosis.
Database	・ Gene ID: 10673 TNFSF13B ・ UniProt: Q9Y275 TNFSF13B

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