抗SV40 T-antigen [PAb416]抗体 | Anti-SV40 T-antigen [PAb416] antibody

• 2025/11/04

  試薬 特別価格

  [GNT]一次抗体製品25％OFFキャンペーン[～2026/02/27]

  期間：2025/11/04 ～2026/02/27

  ダウンロード

  GeneTex International Corporation（GNT）

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	PAb416
Isotype	IgG2a
Application	WB, ICC/IF, IHC-P, IHC-Fr, IP
Reactivity	Simian virus 40

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APPLICATION

Application Note

For IF: Use at a concentration of 1 - 5 μg/ml. For IP: Use at a concentration of 1 - 5 μg/ml. For WB: Use at a concentration of 1 - 5 μg/ml. Predicted molecular weight: 82 kDa and 20 kDa. Optimal dilutions/concentrations should be determined by the researcher.

Positive Control	SV80 or SV-T2 cells
Specificity/Sensitivity	GTX16879 recognizes the 94 kDa SV40 large T antigen and the 20.5 kDa SV40 small T antigen.

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PROPERTIES

Form	Liquid
Buffer	50mM Sodium phosphate, 0.2% gelatin with 0.1% sodium azide as preservative
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration	0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen	Full length protein (purified) (SV40).
Purification	Affinity purified with antigen
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Simian virus 40 T antigen ( Large T) , SV40 virus T antigen ( Large T)
Cellular Localization	Nuclear
Background	SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Jeffers-Francis LK et al. Antiviral Res 2015; 118 : 46-55 Effect of Leflunomide, * and * on replication of BKPyV in a salivary gland in vitro culture system.	Application : WB Reactivity : Simian virus 40
Burger-Calderon R et al. J Virol 2014; 88 (1) : 559-73 Replication of oral BK virus in human salivary gland cells.	Application : WB
Wang J et al. Arch Toxicol 2014; 89 (11) : 2015-25 Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models.	Application : WB
Jeffers LK et al. J Cancer Ther 2013; 4 (3) Correlation of transcription of MALAT-1, a novel noncoding RNA, with deregulated expression of tumor suppressor p53 in small DNA tumor virus models.	Application : WB, IHC-P, IHC-Fr

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