抗Ki67 [SP6]抗体 | Anti-Ki67 [SP6] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	Ki67 antibody [SP6] detects Ki67 protein at nucleus in human cervical metaplasia (left) and carcinoma (right) by immunohistochemical analysis. Sample: Paraffin-embedded human cervix. Ki67 antibody [SP6] (GTX16667) diluted at 1:200.
	Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human colon cancer.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
	Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human cervical carcinoma.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
	Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human breast carcinoma.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
	Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human endometrial carcinoma.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
	Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human ovarian cancer.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
	Ki67 antibody [SP6] detects Ki67 protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human colon cancer.Ki67 stained by Ki67 antibody [SP6] (GTX16667) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

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製品情報

Host	Rabbit
Clonality	Monoclonal
Clone Name	SP6
Isotype	IgG
Application	WB, ICC/IF, IHC-P, IHC-Fr, FACS, IHC
Reactivity	Human, Mouse, Rat, Chicken

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APPLICATION

Application Note

IHC-P: 1:100-1:1000. Staining of formalin-fixed tissues is required by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: 1/200. Predicted molecular weight: 359 kDa. Not tested in other applications

Calculated MW	359 kDa. ( Note )
Positive Control	Tonsil

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PROPERTIES

Form	Liquid
Buffer	Tissue culture supernatant with PBS, BSA, and less than 0.1% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Antigen Species	Human
Purification	Tissue culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Marker Of Proliferation Ki-67 , Kia , Mib- , Mib-1 , Ppp1R105 , Mki67
Cellular Localization	Nuclear
Background	Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67-positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki67 index and histologically low-grade tumours is strong.
Database	・ Gene ID: 4288 ・ UniProt: P46013

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Lu J et al. Exp Cell Res 2020; 387 (1) : 111752 MiR-501-3p functions as a tumor suppressor in non-small cell lung cancer by downregulating RAP1A.	Application : IHC-P Reactivity : Human
Wang YY et al. Biochem Pharmacol 2020; 171 : 113713 Orabase-formulated gentian violet effectively improved oral potentially malignant disorder in vitro and in vivo.	Application : WB Reactivity : Human
Burocziova M et al. Cell Death Dis 2019; 10 (11) : 818 Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.	Application : WB, IHC-P Reactivity : Mouse
Ng WH et al. Int J Mol Sci 2019; 20 (22) Human Wharton's Jelly-Derived Mesenchymal Stem Cells Minimally Improve the Growth Kinetics and Cardiomyocyte Differentiation of Aged Murine Cardiac c-kit Cells in In Vitro without Rejuvenating Effect.	Application : ICC/IF Reactivity : Mouse
Zhou Y et al. J Control Release 2019; 316 : 93-104 Injectable extracellular vesicle-released self-assembling peptide nanofiber hydrogel as an enhanced cell-free therapy for tissue regeneration.	Application : IHC-Fr Reactivity : Mouse

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