抗Bax抗体 | Anti-Bax antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Sheep
Clonality	Polyclonal
Isotype	IgG
Application	IP
Reactivity	Human

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APPLICATION

Application Note

IP: Use at an assay dependent dilution. Is unsuitable for WB. Will not detect denatured protein. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	21 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Preservative: 0.08% Sodium Azide. Constituents: PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic peptide: LTTAPAPPSLPPATPLGPWAFWSRSQWC, corresponding to amino acids 172-199 of Human beta Bax.
Purification	Protein G purified This antibody is provided as a 0.2 μm sterile filtered solution.
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Bcl2 Associated X, Apoptosis Regulator , Bcl2L4 , Bax
Cellular Localization	Cytoplasmic
Background	beta Bax is encoded by a 1.5 kb RNA species created by the retention of intron 5 in the Bax mRNA transcript. The exon4/intron5 splice junction is evolutionarily conserved and is found in both the human and mouse Bax coding regions. The 630 bp intron 5 contributes 60 amino acids to the beta Bax protein before a stop codon is encountered during translation. The beta Bax protein is 24 kDa in size and although it contains the BH1, BH2, and BH3 domains identical to Bax, it has a unique carboxyl terminus and does not have a hydrophobic transmembrane domain. beta Bax mRNA has been found in many mouse tissues using RT-PCR. It is found co-expressed with alpha Bax in lung, stomach, kidney, thymus, lymph node, bone marrow, pancreas, and spleen. beta Bax mRNA was very abundant in brain and duodenum with almost no alpha Bax mRNA detected in these tissues.
Database	・ Gene ID: 581 ・ UniProt: Q07812

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