抗p53抗体 | Anti-p53 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Each lane contains 50μg of total cellular protein separated by 10% SDS-PAGE. (1) Murine mutant p53; (2) murine wild-type p53; (3) wild-type p53 protein from human colorectal carcinoma cells (RKO); (4) elevated levels of human p53 protein following treatment of RKO cells with adriamycin (0.2 μm).

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製品情報

Host	Sheep
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, IP
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

IHC-P: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a concentration of 1 - 10 μg/ml. Predicted molecular weight: 53 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW	44 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Preservative: 0.08% Sodium Azide. Constituents: PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Fusion protein, corresponding to amino acids 1-393 of Human p53.
Purification	Purified by Ammonium Sulfate precipitation.This antibody is provided as a 0.2μm sterile filtered solution.
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Tumor Protein P53 , Bcc7 , Lfs1 , P53 , Trp53 , Tp53
Cellular Localization	Cytoplasmic and Nuclear
Background	p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.
Database	・ Gene ID: 7157 ・ UniProt: P04637

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