抗Cytochrome P450 3A4 + 3A5 [F24 P2 B10]抗体 | Anti-Cytochrome P450 3A4 + 3A5 [F24 P2 B10] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	ICC/IF analysis of HepG2 cells using GTX15836 Cytochrome P450 3A4 + 3A5 antibody [F24 P2 B10]. Panel e is a no primary antibody control.Green : Primary antibodyBlue : NucleiRed : ActinFixation : 4% paraformaldehydePermeabilization : 0.1% Triton X-100 for 10 minuteDilution : 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature
	WB analysis of whole cell extracts (30 μg lysate) of Mouse Liver (Lane 1), Rat Liver (Lane 2), Mouse Brain (Lane 3), Rat Brain (Lane 4) and Mouse Kidney (Lane 5) using GTX15836 Cytochrome P450 3A4 + 3A5 antibody [F24 P2 B10]. Dilution : 1:100-1:1000

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	F24 P2 B10
Isotype	IgG1
Application	WB, ICC/IF, IHC
Reactivity	Human, Mouse, Bovine

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500
ICC/IF	1:250
IHC	Assay dependent

Not tested in other applications.

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PROPERTIES

Form	Liquid
Buffer	Ascites, 0.05% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species	Human
Immunogen	Synthetic peptide corresponding to residues E S R D G T V S G A, conjugated to ovalbumin.
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	cytochrome P450 family 3 subfamily A member 4 , cytochrome P450 family 3 subfamily A member 5 , CP33 , CP34 , CYP3A , CYP3A3 , CYPIIIA3 , CYPIIIA4 , HLP , NF-25 , P450C3 , P450PCN1 , CP35 , CYPIIIA5 , P450PCN3 , PCN3
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]
Database	・ Gene ID: 1576 CYP3A4 ・ Gene ID: 1577 CYP3A5 ・ UniProt: P08684 CYP3A4 ・ UniProt: P20815 CYP3A5

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