抗RANK抗体 | Anti-RANK antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human mammary cancer tissue using GTX11697 RANK antibody.
	WB analysis of various samples using GTX11697 RANK antibody.Lane 1 : Recombinant human RANK protein 10ngLane 2 : Recombinant human RANK protein 5ngLane 3 : Recombinant human RANK protein 2.5ng

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.1-0.5μg/ml
IHC-P	0.5-1μg/ml

Not tested in other applications.

Calculated MW	66.03 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	2.5% BSA, 0.45% NaCl, 0.1% Na₂HPO₄, 0.025% Thimerosal, 0.025% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	500 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human RANK(29-44aa QIAPPCTSEKHYEHLG).
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Cellular Localization	Cell membrane,Cell membrane
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
Database	・ Gene ID: 8792 TNFRSF11A ・ UniProt: Q9Y6Q6 TNFRSF11A

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