熱ショックタンパク質関連抗体および組換え体タンパク質製品の豊富なラインナップ NKMAXBio Heat Shock Protein（HSP）研究用抗体／組換え体タンパク質

• FCM：Flow cytometry 
• IC：Immunocytochemistry 
• IF：Immunofluorescence 
• West：Western blot 

使用文献例

• Kon, N., et al., "A small-molecule DS44170716 inhibits Ca2⁺-induced mitochondrial permeability transition.", Sci. Rep., 7(1), 3864 (2017). [PMID:28634393] （Cyclophilin F/PPIF antibody-AT1F5, #ATGA0139, IP;Human）
• Kaiser, F., et al., "Association between circulating levels of heat-shock protein 27 and aggressive periodontitis.", Cell Stress Chaperones, 23(5), 847～856 (2018). [PMID:29766408] （HSP27 antibody-2A5, #AHS0702, ELISA;Human）
• Kaiser, F., et al., "Association between circulating levels of heat-shock protein 27 and aggressive periodontitis.", Cell Stress Chaperones, 23(5), 847～856 (2018). [PMID:29766408] （HSP27 antibody-2A5, #AHS0702, ELISA;Human）
• Oh, J.Y., et al., "Identification of the HSPB4/TLR2/NF-κB axis in macrophage as a therapeutic target for sterile inflammation of the cornea.", EMBO Mol. Med., 4(5):435～448 (2012). [PMID:22359280]（Alpha A Crystallin/CRYAA antibody-c9F2, #ACA0401, WB and ELISA;Human）
• Muinelo-Romay, L., et al., "Identification of α(1,6) fucosylated proteins differentially expressed in human colorectal cancer.", BMC Cancer, 11, 508 (2011). [PMID:22152070] （GP96/HSP90B1/TRA1 antibody-2H3, #ATA0623, WB; Human）
• Zappasodi, R., et al., "Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target.", Blood, 118(16), 4421～4430 (2011). [PMID:21860023]（HSP105α antibody-J1G12, #AHS0827, IP;Human）

使用文献例

• Casola, C., et al., "S100 alone has the same destructive effect on retinal ganglion cells as in combination with HSP 27 in an autoimmune glaucoma model.", J. Mol. Neurosci., 56(1), 228～236 (2015). [PMID:25577368]（Recombinant HSP27 protein, #HSP0503, Human）
• Reinehr, S., et al., "HSP27 immunization reinforces AⅡ amacrine cell and synapse damage induced by S100 in an autoimmune glaucoma model.", Cell Tissue Res., 371(2), 237～249 (2018). [PMID:29064077]（Recombinant HSP27 protein, #HSP0503, Human）
• Grotegut, P., et al., "Destructive Effect of Intravitreal Heat Shock Protein 27 Application on Retinal Ganglion Cells and Neurofilament.", Int. J. Mol. Sci., 21(2), 549 (2020). [PMID:31952234]（Recombinant HSP27 protein-#HSP0503, Human）
• Seo, J.H., et al., "ARD1-mediated HSP70 acetylation balances stress-induced protein refolding and degradation.", Nat. Commun., 7, 12882 (2016). [PMID:27708256]（Recombinant HSP40/DNAJB1 protein-#HSP0701, Human）
• Vilasi, S., et al., "Human HSP60 with its mitochondrial import signal occurs in solution as heptamers and tetradecamers remarkably stable over a wide range of concentrations.", PLoS One., 9(5), e97657 (2014). [PMID:24830947]（Recombinant HSP60 protein-#ATGP2027, Human）
• Marino, C., et al., "HSP60 Protects against Amyloid β Oligomer Synaptic Toxicity via Modification of Toxic Oligomer Conformation.", ACS Chem. Neurosci., 10(6), 2858～2867 (2019). [PMID:31091411]（Recombinant HSP60 protein-#ATGP2027, Human）
• Vilasi, S., et al., "Inhibition of Aβ_1-42 Fibrillation by Chaperonins: Human HSP60 Is a Stronger Inhibitor than Its Bacterial Homologue GroEL.", ACS Chem. Neurosci., 10(8), 3565～3574 (2019). [PMID:31298838]（Recombinant HSP60 protein-#ATGP2027, Human）
• Kaiser, F., et al., "Monocyte cytokine synthesis in response to extracellular cell stress proteins suggests these proteins exhibit network behaviour.", Cell Stress Chaperones., 19(1), 135～144 (2014). [PMID:23775284]（Recombinant HSP10-#HSP0801, HSP27-#HSP0503, HSP60-#HSP0802) and HSP70 proteins-#HSP0603, Human）
• Kim, Y.H., et al., "Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion.!", Autophagy, 17(9), 2345～2362 (2021). [PMID:33017561]（Recombinant HSP90α protein-#HSP0501, Human）
• Yoshiike, Y., et al., "Amyloid Oligomer Conformation in a Group of Natively Folded Proteins.", PLoS One, 3(9), e3235 (2008). [PMID:18800165]（Recombinant HSP104 protein-#HSP0502, Human）
• Kim, K., et al., "Recombinant human Cyclophilin A stimulates hair follicle cells via Wnt/β-catenin signaling pathway.", Biotechnol. Lett., 41(12), 1451～1458 (2019). [PMID:31655924]（Recombinant Cyclophilin A/PPIA protein-#CYP0702, Human）
• Tsuda, T., et al., "Rho-associated protein kinase and cyclophilin a are involved in inorganic phosphate -induced calcification signaling in vascular smooth muscle cells.", J. Pharmacol. Sci., 142(3), 109～115 (2020). [PMID:31882204]（Recombinant Cyclophilin A/PPIA protein-#CYP0702, Human）
• Kon, N., et al., "A small-molecule DS44170716 inhibits Ca²⁺-induced mitochondrial permeability transition.", Sci. Rep., 7(1), 3864 (2017). [PMID:28634393]（Recombinant Cyclophilin D/Cyclophilin F/PPIF protein-#PPF0901, Human）