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(セルベースアッセイに有用なiPS細胞について)

ATCC®ウェビナーのお知らせ
(セルベースアッセイに有用なiPS細胞について)

掲載日情報:2020/05/27 現在Webページ番号:69422

ATCC®(メーカー略称:ACC)では 2020年6月5日に無料のウェビナーを開催しました。ATCC®Webにて、録画版をご覧になれますので、是非ご覧いただき、皆様の今後のご研究にお役立て下さい。

・演題:Expand Your Cell-based Assays With an Unlimited, Biologically Relevant Resource
・演者:Brian Shapiro, Ph.D., Scientific Content Specialist, ATCC
・言語:英語
・開催日:2020年6月5日(金)2:00 am(日本時間)(開催済み)

ウェビナーの詳細、録画版のご視聴はこちらから

ATCCウェビナーの詳細ページ

Abstract:
Toxicology and cancer researchers alike are challenged by the lack of a consistent source of cells with high physiological relevance for their cell-based assays. The source tissue for primary cells comes from a variety of donors, which can introduce interexperimental variability and confound experimental results. Differentiated induced pluripotent stem cell (iPSC)-derived cells fulfill the need for a consistent source of cells and physiological relevance. iPSCs are able to be generated in large cell numbers from a single clone, providing the needed consistency. Further, iPSCs can be differentiated into a variety of desired, functional cell types, affording the necessary biological relevance. Here we provide data demonstrating how differentiated iPSC-derived cells can be incorporated into immunoassays or further differentiated into cell types such as osteocytes, chondrocytes, and adipocytes.

Key takeaways:

  • Differentiated iPSCs lend the ability to run large toxicity studies and drug screens on highly biologically relevant cells.
  • ATCC iPSCs were used as the source for three types of differentiated cells: CD34+ progenitors, mesenchymal stem cells (MSCs), and monocytes.
  • ATCC R&D scientists have generated in-depth data showing the iPSC-derived cells can be incorporated into immunoassays and further differentiated into cell types such as osteocytes, chondrocytes, and adipocytes.



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