抗TRIF/TICAM1抗体 | Anti-TRIF/TICAM1 Antibody

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Image

	Western Blot: TRIF/TICAM1 Antibody [NBP1-77221] - Analysis of TRIF in human lung lysate with TRIF antibody at (A) 1 and (B) 2 ug/mL.
	Immunohistochemistry-Paraffin: TRIF/TICAM1 Antibody [NBP1-77221] - Human lung tissue with TRIF antibody at 10 ug/ml.
	Western Blot: TRIF/TICAM1 Antibody [NBP1-77221] - Human lung cell lysates with TRIF antibody at (A) 2 and (B) 4 ug/ml.
	Immunofluorescence: TRIF/TICAM1 Antibody [NBP1-77221] - Immunofluorescence of TRIF in Human Lung cells with TRIF antibody at 10 ug/mL.

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Background

TRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3. TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB.

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