抗Kallikrein 3/PSA抗体 | Anti-Kallikrein 3/PSA Antibody

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価格

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Image

	Western Blot: Prostate Specific Antigen Antibody [NBP1-67675] - Upper Panel: Analysis of IP complexes obtained from dendritic cell lysates electroporated with RNAs using anti-HA tag antibodies. Lower Panel: Analysis of IP complexes with specific antibodies, indicated on the right. Lanes Old: using RNA amplified via old amplification protocol from HA-tagged RNA-RCC mix. Lanes New: using RNA amplified via new amplification protocol from HA-tagged RNA-RCC mix. Plus/minus symbols at the top of the panel indicate the presence or absence of CD40L RNA in the RNA mix, respectively. Lane NC: using RCC RNA alone amplified via new protocol. Lane PC: using a mixture of the four model antigen RNAs transcribed in vitro and not amplified. Image provided via product review by verified customer.
	Immunohistochemistry-Paraffin: Prostate Specific Antigen Antibody [NBP1-67675] - Analysis of paraffin-embedded human prostate carcinoma tissue, using Prostate Specific Antigen Antibody. The picture on the right is treated with the synthesized peptide.
	Western Blot: Prostate Specific Antigen Antibody [NBP1-67675] - Analysis of extracts from mouse heart cells, using Prostate Specific Antigen Antibody. The lane on the right is treated with the synthesized peptide.

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Background

Prostate-specific antigen (PSA, Kallikrein-3, KLK3) is a serine protease that is usually secreted from the prostate gland and presented in seminal plasma. PSA function in the liquefaction of seminal coagulum, through hydrolysis of the high molecular mass seminal vesicle protein. Its substrates includes semenogelin I & II, fibronectin, insulin-like growth factor binding protein 3 (IGBP3), and laminin (1). Highly expressed by normal and malignant prostate cancer cells, PSA has been implicated in the growth, invasion, and metastasis of prostate cancer cells (2). Therefore, PSA is widely used as a diagnostic marker for prostate cancer. Recently, PSA has been suggested as an endothelial cell-specific inhibitor of angiogenesis (3).

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