抗Inhibin beta A抗体 | Anti-Inhibin beta A Antibody

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Image

	Western Blot: Inhibin beta A Antibody [NB110-61019] - Analysis in A549 cells were subjected to SDS PAGE followed by western blot at dilution of 1:1000
	Immunocytochemistry/Immunofluorescence: Inhibin beta A Antibody [NB110-61019] - Analysis of A549 cells at dilution of 1:50
	Immunohistochemistry-Paraffin: Inhibin beta A Antibody [NB110-61019] - IHC analysis of Inhibin beta A in mouse colon tissue sections. Image courtesy of product review submitted by Linda Gutierrez.
	Western Blot: Inhibin beta A Antibody [NB110-61019] - Mouse brain were subjected to SDS PAGE followed by western blot with affinity purified Ab at dilution of 1:800.
	Immunocytochemistry/Immunofluorescence: Inhibin beta A Antibody [NB110-61019] - Analysis of Hela cells.
	Immunocytochemistry/Immunofluorescence: Inhibin beta A Antibody [NB110-61019] - Analysis of A549 cells at dilution of 1:50
	Immunohistochemistry: Inhibin beta A Antibody [NB110-61019] - Immunohistochemical staining of formalin-fixed paraffin-embedeed prostate cancer showing Extracellular staining, with affinity purified Ab. Dilution: 1:100.
	Immunohistochemistry-Paraffin: Inhibin beta A Antibody [NB110-61019] - Immunohistochemistry of paraffin-embedded human lung cancer at Dilution 1:50 (under 40x lens).
	Immunohistochemistry-Paraffin: Inhibin beta A Antibody [NB110-61019] - Immunohistochemistry of paraffin-embedded human lung cancer at Dilution 1:50 (under 10x lens).

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Background

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

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