抗Mouse IL-17 Fluorescein抗体(Anti-Mouse IL-17 Fluorescein antibody)

掲載日情報:2018/11/26 現在Webページ番号:34233

Mouse IL-17 Fluoresceinに対する抗体(Anti-Mouse IL-17 Fluorescein )です。
本製品は研究用です。研究用以外には使用できません。

価格

[在庫・価格 :2024年06月07日 13時15分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
詳細 商品名
  • 商品コード
  • メーカー
  • 包装
  • 価格
  • 在庫
  • 法規制等
納期 文献数
Anti-Mouse IL-17 Fluorescein Affinity Purified Polyclonal Ab (100 TESTS)
中止
本製品は取扱中止になりました 1
  • 使用文献
  • メーカーサイト
  • お問い合わせ
説明文
Genbank No: 3605
Protein Accession No: Q62386
法規制等
保存条件 法規備考
抗原種 Mouse 免疫動物 Goat クラス IgG 標識 FITC
交差性 Mouse 適用 FCM
クロナリティ Polyclonal フォーマット 性状 Antigen Affinity Purified 吸収処理
掲載カタログ

製品記事 IL-17 Antibodies for Flow Cytometry
M1/M2 Macrophage Activation Marker
関連記事

[在庫・価格 :2024年06月07日 13時15分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

Anti-Mouse IL-17 Fluorescein Affinity Purified Polyclonal Ab (100 TESTS)

文献数: 1

  • 商品コード:IC421F
  • メーカー:RSD
  • 包装:100tests
  • 本製品は取扱中止になりました

説明文 Genbank No: 3605
Protein Accession No: Q62386
法規制等
保存条件 法規備考
抗原種 Mouse 免疫動物 Goat
交差性 Mouse 適用 FCM
標識 FITC 性状 Antigen Affinity Purified
吸収処理 クラス IgG
クロナリティ Polyclonal フォーマット
掲載カタログ

製品記事 IL-17 Antibodies for Flow Cytometry
M1/M2 Macrophage Activation Marker
関連記事
中止



目次に戻る

Product Details

Species ReactivityMouse
LabelFluorescein
ImmunogenE. coli-derived recombinant mouse IL‑17Thr22-Ala158Accession # Q62386
SourcePolyclonal Goat IgG
PurificationAntigen Affinity-purified
SpecificityDetects mouse IL-17 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human IL-17A and recombinant mouse (rm) IL-17F is observed and less than 1% cross-reactivity with rmIL-17B, rmIL-17C, rmIL‑17D, and rmIL-17E is observed.


目次に戻る

Applications and Data

 Recommended
Concentration
Sample
Intracellular Staining by Flow Cytometry10 µL/106 cellsSee below


Intracellular Staining by Flow Cytometry
Detection of IL‑17/IL‑17A in ActivatedEL‑4 Mouse Cell Line by Flow Cytometry.
Activated EL‑4 mouse lymphoblast cell line was stained with Goat Anti-MouseIL‑17/IL‑17A Fluorescein‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # IC421F, filled histogram) or isotype control antibody (Catalog # IC108F, open histogram). Cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.


目次に戻る

Related Product & Information

Long NameInterleukin 17
BackgroundIL-17/IL-17A
background_contentBackground:
IL-17/IL-17A
Interleukin 17, also known as IL-17A and CTLA-8, was initially identified as a 17 kDa, secreted T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpesvirus Saimiri. Mouse IL-17 cDNA encodes a 158 amino acid (aa) residue precursor protein with a 25 amino acid residue signal peptide that is cleaved to yield the 133 aa residue mature IL-17. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 is also known to form a heterodimer with IL-17F. At the amino acid level, mIL-17 shows 62% and 87% aa sequence identity with human and rat IL-17, respectively. The receptor for the IL-17A homodimer and IL-17A:F heterodimer is reported to be a combinationof IL-17 RA and IL-17 RC, with a possible contribution by IL-17 RD. The expression of IL-17 is widespread, and found associated with LTi cells, B cells, gamma δ T cells, CD4+ Th17 cells, iNKT cells, neutrophils, intestinal Paneth cells, Type I ILCs and CD8+ Tc17 cells. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-kappa B and costimulation of T cell proliferation, the preservation of intestinal mucosal integrity, and the induction of antimicrobial peptides by epithelium.


目次に戻る

Citations

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
  1. Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis
    Authors: EN Komegae, TA Souza, LZ Grund, C Lima, M Lopes-Ferr
    PLoS ONE, 2017;12(2):e0171796.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow



目次に戻る

お問い合わせ先

(テクニカルサポート 試薬担当)

reagent@funakoshi.co.jp

製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。