抗Human CD31/PECAM-1 Phycoerythrin抗体(Anti-Human CD31/PECAM-1 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	Activated HUVEC human umbilical vein endothelial cells
Source	Monoclonal Mouse IgG1 Clone # 9G11
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human CD31/PECAM‑1 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) E‑Selectin, rhICAM-1, -2, -3, rhVCAM-1, or recombinant mouse VCAM-1 is observed.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CD31/PECAM‑1 in Human Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CD31/PECAM‑1 PE‑conjugated Monoclonal Antibody (Catalog # FAB3567P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Platelet Endothelial Cell Adhesion Molecule 1
Background	CD31/PECAM-1
background_content	Background: CD31/PECAM-1 The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin alpha v beta 3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.

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Citations

1. Human kallikrein-related peptidase 12 stimulates endothelial cell migration by remodeling the fibronectin matrix
   Authors: T Kryza, C Parent, J Pardessus, A Petit, J Burlaud-Ga, P Reverdiau, S Iochmann, V Labas, Y Courty, N Heuzé-Vour
   Sci Rep, 2018;8(1):6331.
   Species: Human
   Sample Type: Whole Cells
   Application: ICC


2. Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.
   Authors: Norton, Kerri-An, Han, Zheyi, Popel, Aleksand, Pandey, Niranjan
   Onco Targets Ther, 2014;7(0):1571-82.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies.
   Authors: Frassanito M, Rao L, Moschetta M, Ria R, di Marzo L, De Luisi A, Racanelli V, Catacchio I, Berardi S, Basile A, Menu E, Ruggieri S, Nico B, Ribatti D, Fumarulo R, Dammacco F, Vanderkerken K, Vacca A
   , 2014;0(0):.
   Species: Human
   Sample Type: Cell Lysates
   Application: Flow


4. Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway.
   Authors: Kryza T, Achard C, Parent C, Marchand-Adam S, Guillon-Munos A, Iochmann S, Korkmaz B, Respaud R, Courty Y, Heuze-Vourc'h N
   FASEB J, 2014;28(2):740-51.
   Species: Human
   Sample Type: Whole Tissue
   Application: IHC


5. Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium.
   Authors: Albert R, Vereb Z, Csomos K, Moe M, Johnsen E, Olstad O, Nicolaissen B, Rajnavolgyi E, Fesus L, Berta A, Petrovski G
   PLoS ONE, 2012;7(10):e47187.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Signaling hierarchy regulating human endothelial cell development.
   Authors: Kelly MA, Hirschi KK
   Arterioscler. Thromb. Vasc. Biol., 2009;29(5):718-24.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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