抗Human KIR2DL3/CD158b2 Fluorescein抗体(Anti-Human KIR2DL3/CD158b2 Fluorescein antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Fluorescein
Immunogen	BaF3 mouse pro-B cell line transfected with human KIR2DL3/CD158b2Accession # P43628
Source	Monoclonal Mouse IgG2A Clone # 180701
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human KIR2DL3/CD158b2. Stains BaF3 cells transfected with human KIR2DL3 in flow cytometry. Does not stain BaF3 cells transfected with KIR2DL1, 2DL2, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of KIR2DL3/CD158b2 inHuman PBMCs by Flow Cytometry. Human peripheral blood mononuclearcells (PBMCs) were stained with Mouse Anti-Human KIR2DL3/CD158b2Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB2014F) andMouse Anti-Human NCAM‑1/CD56 PE‑conjugated MonoclonalAntibody (Catalog # FAB2408P).View our protocol for StainingMembrane-associated Proteins.

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Related Product & Information

Long Name	Killer Cell Immunoglobulin-like Receptor, Two Domain Long Cytoplasmic Tail, 3
Background	KIR2DL3/CD158b2
background_content	Background: KIR2DL3/CD158b2 KIR2DL3 is one of several immunoglobulin-like receptors expressed on NK and T cells that bind MHC class I molecules and regulate killer cell activity. KIR2DL3 interacts specifically with HLA-Cw3.

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Citations

1. 2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.
   Authors: Dunphy S, Guinan K, Chorcora C, Jayaraman J, Traherne J, Trowsdale J, Pende D, Middleton D, Gardiner C
   Genes Immun, 2015;16(5):301-10.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
   Authors: Marquardt N, Beziat V, Nystrom S, Hengst J, Ivarsson M, Kekalainen E, Johansson H, Mjosberg J, Westgren M, Lankisch T, Wedemeyer H, Ellis E, Ljunggren H, Michaelsson J, Bjorkstrom N
   J Immunol, 2015;194(6):2467-71.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT.
   Authors: Holmes T, Wilson E, Black E, Benest A, Vaz C, Tan B, Tanavde V, Cook G
   Proc Natl Acad Sci U S A, 2014;111(52):E5688-96.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
   Authors: Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
   Eur J Immunol, 2013;43(2):480-7.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Molecular characterisation of KIR2DS2*005, a fusion gene associated with a shortened KIR haplotype.
   Authors: Ordonez D, Gomez-Lozano N, Rosales L, Vilches C
   Genes Immun., 2011;12(7):544-51.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.
   Authors: Bjorkstrom NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M, Michaelsson J, Malmberg KJ, Klingstrom J, Ahlm C, Ljunggren HG
   J. Exp. Med., 2011;208(1):13-21.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs.
   Authors: Beziat V, Descours B, Parizot C, Debre P, Vieillard V
   PLoS ONE, 2010;5(8):e11966.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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