抗Mouse CXCR2 Phycoerythrin抗体(Anti-Mouse CXCR2 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Mouse
Label	Phycoerythrin
Immunogen	C6 rat glioma cell line transfected with mouse CXCR2Met1-Leu359Accession # P35343
Source	Monoclonal Rat IgG2A Clone # 242216
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Stains mouse CXCR2-transfected cells but not CXCR1 transfectants.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CXCR2/IL‑8 RB in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse Gr‑1/Ly‑6G APC‑conjugated Monoclonal Antibody (Catalog # FAB1037A) and either (A) Rat Anti-Mouse CXCR2/IL‑8 RB PE‑conjugated Monoclonal Antibody (Catalog # FAB2164P) or (B) Rat IgG1 Phycoerythrin Isotype Control (Catalog # IC005P). View our protocol for Staining Membrane-associated Proteins.
Flow Cytometry
	Detection of CXCR2/IL‑8 RB in HEK293 Human Cell Line Transfected with Mouse CXCR2/IL-8 RB and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse CXCR2/IL-8 RB or (B) mouse CXCR1/IL-8 RA and eGFP was stained with Rat Anti-Mouse CXCR2/IL‑8 RB PE‑conjugated Monoclonal Antibody (Catalog # FAB2164P). Quadrant markers were set based on control antibody staining (Catalog # IC005P). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Interleukin 8 Receptor B
Background	CXCR2/IL-8 RB
background_content	Background: CXCR2/IL-8 RB CXCR2, also known as IL-8 RB, is a G protein-coupled chemokine receptor expressed on neutrophils. It binds IL-8, GRO alpha, GRO beta, GRO gamma, NAP-2, and ENA-78.

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Citations

1. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes
   Authors: X Wu, KK Dayanand, RP Thylur, CC Norbury, DC Gowda
   J. Biol. Chem., 2017;0(0):.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


2. IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model
   Authors: J Xu, J Guardado, R Hoffman, H Xu, R Namas, Y Vodovotz, L Xu, M Ramadan, J Brown, HR Turnquist, TR Billiar
   PLoS Med., 2017;14(7):e1002365.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


3. CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer
   Authors: D Wang, H Sun, J Wei, B Cen, RN DuBois
   Cancer Res., 2017;0(0):.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


4. Mincle activation enhances neutrophil migration and resistance to polymicrobial septic peritonitis
   Authors: WB Lee, JJ Yan, JS Kang, Q Zhang, WY Choi, LK Kim, YJ Kim
   Sci Rep, 2017;7(0):41106.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


5. Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process
   Authors: Pedro Luiz Rosalen
   Phytomedicine, 2016;23(13):1583-1590.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


6. A Broad-Spectrum Chemokine-Binding Protein of Bovine Papular Stomatitis Virus Inhibits Neutrophil and Monocyte Infiltration in Inflammatory and Wound Models of Mouse Skin
   PLoS ONE, 2016;11(12):e0168007.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


7. B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration
   Sci Rep, 2016;6(0):31284.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


8. CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice.
   Authors: Citro A, Valle A, Cantarelli E, Mercalli A, Pellegrini S, Liberati D, Daffonchio L, Kastsiuchenka O, Ruffini P, Battaglia M, Allegretti M, Piemonti L
   Diabetes, 2015;64(4):1329-40.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


9. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
   Authors: Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F
   Mucosal Immunol, 2014;7(5):1079-93.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


10. alpha-Acid glycoprotein decreases neutrophil migration and increases susceptibility to sepsis in diabetic mice.
    Authors: Spiller F, Carlos D, Souto FO, de Freitas A, Soares FS, Vieira SM, Paula FJ, Alves-Filho JC, Cunha FQ
    Diabetes, 2012;61(6):1584-91.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow

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