抗TNF Receptor Ⅲ抗体(Anti-TNF Receptor Ⅲ, Mouse-Mono antibody)
掲載日情報:2019/10/21 現在Webページ番号:30467
TNF Receptor Ⅲに対する抗体(Anti-TNF Receptor Ⅲ, Mouse-Mono )です。
※ 本製品は研究用です。研究用以外には使用できません。
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価格
[在庫・価格 :2026年04月06日 20時55分現在]
| 詳細 | 商品名 |
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文献数 | ||
|---|---|---|---|---|---|
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Anti-TNF Receptor III, Mouse-Mono(71319) <Anti-Lymphotoxin β Receptor> <Anti-TNFRSF3> |
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1 | |||
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Anti-Human Lymphotoxin beta R/TNFRSF3 MAb (Clone 71319) |
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1 | |||
[在庫・価格 :2026年04月06日 20時55分現在]
Anti-TNF Receptor III, Mouse-Mono(71319) <Anti-Lymphotoxin β Receptor> <Anti-TNFRSF3>
文献数: 1
- 商品コード:MAB629
- メーカー:RSD
- 包装:500μg
- 価格:¥95,000
- 在庫:1個
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
Anti-Human Lymphotoxin beta R/TNFRSF3 MAb (Clone 71319)
文献数: 1
- 商品コード:MAB629-SP
- メーカー:RSD
- 包装:25μg
- 価格:¥25,000
- 在庫:無(未発注)
- 納期:2~3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
追加しました。
Product Details
| Species Reactivity | Human |
|---|---|
| Label | Unconjugated |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Lymphotoxin beta R/TNFRSF3Gln31-Met227Accession # P36941 |
| Source | Monoclonal Mouse IgG1 Clone # 71319 |
| Purification | Protein A or G purified from hybridoma culture supernatant |
| Specificity | Detects human Lymphotoxin beta R/TNFRSF3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFas, rhGITR, rhHVEM, recombinant mouse (rm) Lymphotoxin beta R, rhNGF R, rhOPG, rhRELT, rhTAJ, rhTNF RI or rhTNF RII is observed. |
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Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 1 µg/mL | Recombinant Human Lymphotoxin beta R/TNFRSF3 Fc Chimera (Catalog # 629-LR) |
| Flow Cytometry | 2.5 µg/106 cells | Human whole blood monocytes |
| CyTOF-ready | Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation. | |
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Related Product & Information
| Background | Lymphotoxin beta R/TNFRSF3 |
|---|---|
| background_content | Background: Lymphotoxin beta R/TNFRSF3 Lymphotoxin beta receptor (LT beta R), also known as TNF RIII and TNF R-related protein (TNF Rrp) is a member of the TNF receptor superfamily, designated TNFRSF3. Human LT beta R cDNA encodes a 435 amino acid (aa) residue type I membrane protein with a putative 30 aa residue signal peptide, a 193 aa residue extracellular domain and a 171 aa residue cytoplasmic domain. The extracellular domain of LT beta R contains four cysteine-rich motifs characteristic of the TNF receptor superfamily. The cytoplasmic region of LT beta R shares little sequence similarity with other TNF receptor family members, suggesting that different signaling mechanisms may be used. LT beta R is expressed in a variety of tissues including visceral and lymphoid tissues. LT beta R is also expressed by cell lines of monocytic, epithelial, and fibroblastic origins but not by T and B lymphocytes. Human and mouse LT beta R share 76% aa sequence homology. The TNF family ligands that have been shown to bind and activate LT beta R include LIGHT (also a ligand for HVEM) and the heterotrimeric lymphotoxin LT alpha 1/ beta 2 or LT alpha 2/ beta 1. Depending on the cell type, activation of LT beta R has been shown to induce NF kappa B activation, chemokine production, growth arrest, and apoptosis. In vivo, LT beta R has been shown to play a critical role in controlling cellular immune functions and lymphoid organogenesis. |
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Citations
- LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes.
Authors: Kang YM, Kim SY, Kang JH
Arthritis Rheum., 2007;56(4):1106-17.
Species: Human
Sample Type: Whole Cells
Application: Flow
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