抗Human CXCR5 Fluorescein抗体(Anti-Human CXCR5 Fluorescein antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Fluorescein
Immunogen	NS0 mouse myeloma cell line transfected with human CXCR5Met1-Phe372Accession # P32302
Source	Monoclonal Mouse IgG2B Clone # 51505
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Stains human CXCR5 transfectants but not the parental cell lines in flow cytometry. Does not cross-react with human CXCR2, CXCR3, or CXCR4 transfectants.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of CXCR5 in Human Peripheral Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A) and either (A) Mouse Anti-Human CXCR5 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB190F) or (B) Mouse IgG2B Fluorescein Isotype Control (Catalog # IC0041F). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	643 (Human); 12145 (Mouse); 29363 (Rat)
Background	CXCR5
background_content	Background: CXCR5 CXCR5, also known as BLR-1, is a 7 transmembrane domain protein expressed on B cells. CXCR5 mediates B cell migration following binding of CXCL13.

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Citations

1. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity
   Authors: Zaidoon Al-Jaderi
   Front Immunol, 2016;7(0):437.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients.
   Authors: Kaltenmeier C, Gawanbacht A, Beyer T, Lindner S, Trzaska T, van der Merwe J, Harter G, Gruner B, Fabricius D, Lotfi R, Schwarz K, Schutz C, Honig M, Schulz A, Kern P, Bommer M, Schrezenmeier H, Kirchhoff F, Jahrsdorfer B
   J Immunol, 2015;194(8):3768-77.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. CXCR5(+) T helper cells mediate protective immunity against tuberculosis.
   Authors: Slight S, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko B, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart T, Randall T, Khader S
   J Clin Invest, 2013;123(2):712-26.
   Species: Human
   Sample Type: Whole Tissue
   Application: IHC Paraffin-embedded


4. CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response.
   Authors: Zhang HH, Song K, Rabin RL, Hill BJ, Perfetto SP, Roederer M, Douek DC, Siegel RM, Farber JM
   J. Immunol., 2010;185(11):6646-63.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients.
   Authors: Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot A, Maurer D
   J. Immunol., 2007;179(6):4272-82.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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