抗Human CXCR2/IL-8 RB Phycoerythrin抗体(Anti-Human CXCR2/IL-8 RB Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	NS0 mouse myeloma cell line transfected with human CXCR2/IL-8 RBMet1-Leu355Accession # AAB25880
Source	Monoclonal Mouse IgG2A Clone # 48311
Purification	Protein A or G purified from ascites
Specificity	Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CXCR2/IL-8 RB in Human Peripheral Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB PE-conjugated Monoclonal Antibody (Catalog # FAB331P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Interleukin 8 Receptor B
Background	CXCR2/IL-8 RB
background_content	Background: CXCR2/IL-8 RB CXCR2, also known as IL-8 RB, is a G protein-coupled chemokine receptor expressed on neutrophils. It binds IL-8, GRO alpha, GRO beta, GRO gamma, NAP-2, and ENA-78.

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Citations

1. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
   Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
   J. Immunol., 2010;184(6):2886-98.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
   Authors: McDermott DH, De Ravin SS, Jun HS
   Blood, 2010;116(15):2793-802.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
   Authors: Ahern D, Lloyd CM, Robinson DS
   Allergy, 2009;64(8):1121-9.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
   Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
   J. Neuroimmunol., 2008;199(1):35-45.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.
   Authors: Traves SL, Smith SJ, Barnes PJ, Donnelly LE
   J. Leukoc. Biol., 2004;76(2):441-50.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
   Authors: Liu LY, Jarjour NN, Busse WW, Kelly EA
   J. Allergy Clin. Immunol., 2003;112(3):556-62.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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