抗Human CXCR1/IL-8 RA Phycoerythrin抗体(Anti-Human CXCR1/IL-8 RA Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	NS0 mouse myeloma cell line transfected with human CXCR1/IL-8 RAMet1-Leu350Accession # AAA59159
Source	Monoclonal Mouse IgG2A Clone # 42705
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CXCR1/IL‑8 RA in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR1/IL‑8 RA PE‑conjugated Monoclonal Antibody (Catalog # FAB330P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Interleukin 8 Receptor A
Background	CXCR1/IL-8 RA
background_content	Background: CXCR1/IL-8 RA The human C-X-C chemokine IL-8 is a potent neutrophil chemotactic and activating factor. Two distinct G protein-linked cell surface receptors, known as IL-8 RA (type I or CXCR1) and IL-8 RB (type II or CXCR2), can interact with the IL-8 molecule. These two receptors share 77% amino acid homology. CXCR1 expression has been documented on neutrophils, monocytes, and a small population of T cells.

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Citations

1. Human trophectoderm apposition is regulated by interferon gamma-induced protein 10 (IP-10) during early implantation.
   Authors: Sela H, Goldman-Wohl D, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S
   Placenta, 2013;34(3):222-30.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
   Authors: Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H
   J Immunol, 2013;190(8):3939-48.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis.
   EMBO J., 2012;31(17):3607-19.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.
   Authors: Vujanovic, Lazar, Ballard, Wenners, Thorne, Stephen, Vujanovic, Nikola L, Butterfield, Lisa H
   Oncoimmunology, 2012;1(4):448-457.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
   Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
   J. Immunol., 2010;184(6):2886-98.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
   Authors: Carbone T, Nasorri F, Pennino D
   J. Immunol., 2010;184(2):1102-10.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
   Authors: McDermott DH, De Ravin SS, Jun HS
   Blood, 2010;116(15):2793-802.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
   Authors: Ahern D, Lloyd CM, Robinson DS
   Allergy, 2009;64(8):1121-9.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


9. Duffy antigen modifies the chemokine response in human endotoxemia.
   Authors: Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B
   Crit. Care Med., 2008;36(1):159-65.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


10. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
    Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
    J. Neuroimmunol., 2008;199(1):35-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow

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