抗ICAM-1抗体(Anti-ICAM-1, Human, Mouse-Mono, FITC antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Fluorescein
Immunogen	Activated HUVEC human umbilical vein endothelial cells
Source	Monoclonal Mouse IgG1 Clone # BBIG-I1 (11C81)
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Stains human ICAM-1/CD54 on human ICAM-1 transfected COS cells. It does not bind COS cells transfected with E-Selectin, VCAM-1, or PECAM-1.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of ICAM‑1/CD54 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 APC‑conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human ICAM‑1/CD54 Fluorescein‑conjugated Monoclonal Antibody (Catalog # BBA20) or (B) Mouse IgG1 Fluorescein Isotype Control (Catalog # IC002F). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Intercellular Adhesion Molecule 1
Background	ICAM-1/CD54
background_content	Background: ICAM-1/CD54 ICAM-1 is a member of the immunoglobulin superfamily whose expression is up‑regulated on leukocytes, epithelial cells and resting endothelial cells in response to inflammatory signals. ICAM-1 binds the leukocyte integrins LFA-1 and Mac-1.

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Citations

1. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
   Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
   Sci Rep, 2018;8(1):1561.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. SIRT1 inhibition causes oxidative stress and inflammation in patients with coronary artery disease
   Authors: SH Chan, CH Hung, JY Shih, PM Chu, YH Cheng, HC Lin, KL Tsai
   Redox Biol, 2017;13(0):301-309.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro
   Authors: A Schaefer, TJ van Duijn, J Majolee, K Burridge, PL Hordijk
   J. Immunol., 2017;0(0):.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Tranexamic acid and the gut barrier: Protection by inhibition of trypsin uptake and activation of downstream intestinal proteases
   Authors: ME Diebel, LN Diebel, DM Liberati
   Am. J. Surg, 2016;0(0):.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
   PLoS ONE, 2016;11(12):e0167361.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of Platelet Microparticles
   Authors: KE Happonen, S Tran, M Mörgelin, R Prince, S Calzavarin, A Angelillo-, B Dahlbäck
   J. Biol. Chem., 2016;291(20):10586-601.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Molecular mechanisms regulating the synergism between IL-32gamma and NOD for the activation of eosinophils.
   Authors: Wong C, Dong J, Lam C
   J Leukoc Biol, 2014;95(4):631-42.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation.
   Authors: Li N, Mao D, Lu S, Tong C, Zhang Y, Long M
   J Immunol, 2013;190(8):4371-81.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


9. Transendothelial migration enables subsequent transmigration of neutrophils through underlying pericytes.
   Authors: Ayres-Sander C, Lauridsen H, Maier C, Sava P, Pober J, Gonzalez A
   PLoS ONE, 2013;8(3):e60025.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


10. TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier.
    Authors: Stephan D, Sbai O, Wen J, Couraud P, Putterman C, Khrestchatisky M, Desplat-Jego S
    J Neuroinflammation, 2013;10(0):9.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow

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