抗TER-119抗体(Anti-TER-119 Erythroid Antigen, Mouse, Rat-Mono antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information

価格

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Product Details

Species Reactivity	Mouse
Label	Unconjugated
Source	Monoclonal Rat IgG2b Clone # TER-119
Specificity	This antibody has been shown to react with cells of the erythroid lineage in embryonic yolk sac, fetal liver, adult bone marrow, adult peripheral blood and adult lymphoid organs.1 TER-119 antigen is a molecule associated with cell-surface glycophorin A.2 The antibody has been shown to react with erythroid cells at differentiation stages from early proerythroblast to mature erythrocyte.2

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Applications and Data

	Recommended Concentration	Sample
Cell depletion	This antibody has been used in combination with antibodies to other lineage markers to deplete the cells of major hematopoietic lineages. Each vial contains sufficient antibody to deplete TER-119 erythroid antigen+ cells from 1 x 109 bone marrow cells.

Cell Depletion
	Cell Depletion Figure 1: Lineage positive bone marrow cells from C57/Bl6 mice were depleted using monoclonal anti-mouse CD3, CD4, CD5, CD8 alpha, CD11b/MAC-1 alpha, B220, Gr-1 (Ly-6G) and TER-119 erythroid antigen antibodies and stained with goat anti-rat IgG PE-conjugated. Flow cytometric analysis was performed A) Before (dotted histogram) and after (solid histogram) the depletion antibody cocktail was added; B) Before (dotted histogram) and after (solid histogram) magnetic depletion using Dynabeads; and C) Expression of CD117 (SCF R/c-kit) (R&D Systems Catalog # MAB1356; dotted histogram) in bone marrow-progenitor cells after enrichment using the mouse lineage panel and bead depletion.
Cell Depletion
	Cell Depletion
Cell Depletion
	Cell Depletion

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Related Product & Information

Background	TER-119
background_content	Background: TER-119 The TER-119 Antigen has been used as a marker for erythroid cells from the early proerythroblast to mature erythrocyte stages of development. The 52-kDa TER-119 Antigen is associated with Glycophorin A on erythrocytes.

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