抗Human BDNF抗体(Anti-Human BDNF antibody)
掲載日情報：2019/10/21 現在Webページ番号：28510
Human BDNFに対する抗体(Anti-Human BDNF )です。
※ 本製品は研究用です。研究用以外には使用できません。
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価格
[在庫・価格 ：2025年04月27日 00時00分現在]
| 詳細 | 商品名 |
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文献数 | ||
|---|---|---|---|---|---|
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Anti-Human BDNF MAb (Clone 37141) |
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1 | |||
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Anti-Human BDNF MAb (Clone 37141) |
|
1 | |||
|
Anti-Human BDNF MAb (Clone 37141) |
|
1 | |||
[在庫・価格 ：2025年04月27日 00時00分現在]
Anti-Human BDNF MAb (Clone 37141)
文献数： 1
- 商品コード：MAB648-100
- メーカー：RSD
- 包装：100μg
- 価格：¥101,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
Anti-Human BDNF MAb (Clone 37141)
文献数： 1
- 商品コード：MAB648-500
- メーカー：RSD
- 包装：500μg
- 価格：¥232,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
Anti-Human BDNF MAb (Clone 37141)
文献数： 1
- 商品コード：MAB648-SP
- メーカー：RSD
- 包装：25μg
- 価格：¥30,000
- 在庫：無(未発注)
- 納期：2～3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
追加しました。
Product Details
| Species Reactivity | Human |
|---|---|
| Label | Unconjugated |
| Immunogen | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human BDNFArg128-Arg247 Accession # P23560 |
| Source | Monoclonal Mouse IgG2A Clone # 37141 |
| Purification | Protein A or G purified from ascites |
| Specificity | Detects human BDNF in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) NT‑3 or rhNT‑4. |
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Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 1 µg/mL | Recombinant Human BDNF (Catalog # 248-BD). Please note: Human BDNF (clone 35928) (Catalog # MAB248) is preferred for this application. |
| ELISA | This antibody functions as an ELISA detection antibody when paired with Mouse Anti-Human BDNF Monoclonal Antibody (Catalog # MAB848R). This product is intended for assay development on various assay platforms requiring antibody pairs. We recommend the Human/Mouse BDNF DuoSet ELISA Kit (Catalog # DY248) for convenient development of a sandwich ELISA. | |
| ELISA | |
|---|---|
 | Human BDNF ELISA Standard Curve. Recombinant Human BDNF protein was serially diluted 2-fold and captured by Mouse Anti-Human BDNF Monoclonal Antibody (Catalog # MAB848R) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human BDNF Monoclonal Antibody (Catalog # MAB648) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994). |
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Related Product & Information
| Background | BDNF |
|---|---|
| background_content | Background: BDNF Brain-derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate the mature proteins. All neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds and all share approximately 55% sequence identity at the amino acid level. Similarly to NGF, bioactive BDNF is predicted to be a non-covalently linked homodimer. BDNF cDNA encodes a 247 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature BDNF. The amino acid sequence of mature BDNF is identical in all mammals examined. High levels of expression of BDNF have been detected in the hippocampus, cerebellum, fetal eye and placenta. In addition, low levels of BDNF expression are also found in the pituitary gland, spinal cord, heart, lung and skeletal muscle. BDNF binds with high affinity and specifically activates the TrkB tyrosine kinase receptor. |
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Citations
- Neuroendocrine cells of nasal mucosa are a cellular source of brain-derived neurotrophic factor.
Authors: Jornot L, Lacroix JS, Rochat T
Eur. Respir. J., 2008;32(3):769-74.
Species: Human
Sample Type: Whole Cells
Application: ICC
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