抗STRO-1抗体(Anti-STRO-1, Human, Mouse-Mono antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

目次に戻る

Product Details

Species Reactivity	Human
Label	Unconjugated
Immunogen	Human CD34+ bone marrow cells
Source	Monoclonal Mouse IgM Clone # STRO-1
Purification	IgM-specific Affinity-purified from hybridoma culture supernatant
Specificity	Detects human STRO-1.

目次に戻る

Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	2.5 µg/106 cells	MG‑63 human osteosarcoma cell line
CyTOF-ready	Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
Immunocytochemistry	8-25 µg/mL	See below

Immunocytochemistry

STRO‑1 in Human MG‑63 Cell Line. STRO‑1 was detected in immersion fixed MG‑63 human osteosarcoma cell line using Human STRO‑1 Monoclonal Antibody (Catalog # MAB1038) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgM Secondary Antibody (red; Catalog # NL019) (Catalog # NL019), and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

目次に戻る

Related Product & Information

Background

STRO-1

background_content

Background: STRO-1 STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units-fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells (1). The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes (2).

目次に戻る

Citations

1. Safety and efficacy of the mesenchymal stem cell in feline eosinophilic keratitis treatment
   Authors: AJ Villatoro, S Claros, V Fernández, C Alcoholado, F Fariñas, A Moreno, J Becerra, JA Andrades
   BMC Vet. Res., 2018;14(1):116.
   Species: Feline
   Sample Type: Whole Cells
   Application: Flow


2. Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNF?
   Authors: N Sasaki, Y Itakura, M Toyoda
   Oncotarget, 2018;9(5):5562-5577.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. ?-Catenin Accumulation Is Associated With Increased Expression of Nanog Protein and Predicts Maintenance of MSC Self-Renewal
   Authors: SJ Yu, HJ Kim, ES Lee, CG Park, SJ Cho, SH Jeon
   Cell Transplant, 2017;26(2):365-377.
   


4. In-vitro characterization of canine multipotent stromal cells isolated from synovium, bone marrow, and adipose tissue: a donor-matched comparative study
   Authors: RN Bearden, SS Huggins, KJ Cummings, R Smith, CA Gregory, WB Saunders
   Stem Cell Res Ther, 2017;8(1):218.
   Species: Canine
   Sample Type: Whole Cells
   Application: Flow


5. Human Dental Pulp Cells Differentiate toward Neuronal Cells and Promote Neuroregeneration in Adult Organotypic Hippocampal Slices In Vitro
   Authors: L Xiao, R Ide, C Saiki, Y Kumazawa, H Okamura
   Int J Mol Sci, 2017;18(8):.
   Species: Human
   Sample Type: Whole Tissue
   Application: IHC Paraffin Emedded


6. A monoclonal antibody recognizes undifferentiation-specific carbohydrate moieties expressed on cell surface of the human dental pulp cells
   Authors: KJ Kang, SY Ko, CJ Ryu, YJ Jang
   Stem Cell Res, 2017;21(0):85-93.
   Species: Human
   Sample Type: Tissue Homogenates
   Application: Flow


7. Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold
   Authors: X Wang, H Xing, G Zhang, X Wu, X Zou, L Feng, D Wang, M Li, J Zhao, J Du, Y Lv, L E, H Liu
   Stem Cells Int, 2016;2016(0):8741641.
   Species: Human
   Sample Type: Whole Cells
   Application: IHC Fresh


8. The differentiation potential of gingival mesenchymal stem cells induced by apical tooth germ cell?conditioned medium
   Mol Med Rep, 2016;14(4):3565-72.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


9. In vivo experimental model of orthotopic dental pulp regeneration under the influence of photobiomodulation therapy
   Authors: Maria Stella Moreira
   J. Photochem. Photobiol. B, Biol, 2016;166(0):180-186.
   Species: Rat
   Sample Type: Whole Tissue
   Application: IHC-P


10. Immobilized WNT Proteins Act as a Stem Cell Niche for Tissue Engineering
    Stem Cell Reports, 2016;7(1):126-37.
    Species: Human
    Sample Type: Whole Cells
    Application: IHC - PFA fixed

目次に戻る