抗Human CXCR1/IL-8 RA Fluorescein抗体(Anti-Human CXCR1/IL-8 RA Fluorescein antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Fluorescein
Immunogen	NS0 mouse myeloma cell line transfected with human CXCR1/IL-8 RAMet1-Leu350Accession # AAA59159
Source	Monoclonal Mouse IgG2A Clone # 42705
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CXCR1/IL‑8 RA in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR1/IL‑8 RA Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB330F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Interleukin 8 Receptor A
Background	CXCR1/IL-8 RA
background_content	Background: CXCR1/IL-8 RA The human C-X-C chemokine IL-8 is a potent neutrophil chemotactic and activating factor. Two distinct G protein-linked cell surface receptors, known as IL-8 RA (type I or CXCR1) and IL-8 RB (type II or CXCR2), can interact with the IL-8 molecule. These two receptors share 77% amino acid homology. CXCR1 expression has been documented on neutrophils, monocytes, and a small population of T cells.

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Citations

1. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity
   Authors: Zaidoon Al-Jaderi
   Front Immunol, 2016;7(0):437.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals.
   Authors: Hazeldine J, Harris P, Chapple I, Grant M, Greenwood H, Livesey A, Sapey E, Lord J
   Aging Cell, 2014;13(4):690-8.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
   Authors: Morandi, Fabio, Di Carlo, Emma, Ferrone, Soldano, Petretto, Andrea, Pistoia, Vito, Airoldi, Irma
   J Immunol, 2014;192(6):2634-42.
   


4. Identification of human NK17/NK1 cells.
   Authors: Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA
   PLoS ONE, 2011;6(10):e26780.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6.
   Authors: Eikawa S, Ohue Y, Kitaoka K
   J. Immunol., 2010;185(11):6734-40.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells.
   Authors: Maxwell PJ, Gallagher R, Seaton A, Wilson C, Scullin P, Pettigrew J, Stratford IJ, Williams KJ, Johnston PG, Waugh DJ
   Oncogene, 2007;26(52):7333-45.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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