抗Human CCR6 Phycoerythrin抗体(Anti-Human CCR6 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	NS0 mouse myeloma cell line transfected with human CCR6Met1-Met374Accession # P51684
Source	Monoclonal Mouse IgG2B Clone # 53103
Purification	Protein A or G purified from ascites
Specificity	Detects human CCR6. Stains human CCR6 transfectants but not the parental cell line in flow cytometry. Does not cross-react with transfectants expressing human CCR1, CCR2, CCR3, CCR4, CCR5, CCR7, CXCR1, CXCR2, CXCR3, CXCR4, or STRL33.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of CCR6 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A) and either (A) Mouse Anti-Human CCR6 PE‑conjugated Monoclonal Antibody (Catalog # FAB195P) or (B) Mouse IgG2B Phycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	1235 (Human); 12458 (Mouse); 308163 (Rat)
Background	CCR6
background_content	Background: CCR6 CCR6 is a seven transmembrane-spanning G protein-coupled receptor that binds the chemokine MIP-3 alpha and mediates the chemoattraction of B and T lymphocytes.

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Citations

1. Effector Vgamma9Vdelta2 T cells dominate the human fetal gammadelta T-cell repertoire.
   Authors: Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, Marchant A, Vermijlen D
   Proc Natl Acad Sci U S A, 2015;112(6):E556-65.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
   Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
   PLoS ONE, 2014;9(9):e106673.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature.
   Authors: Loubaki L, Hadj-Salem I, Fakhfakh R, Jacques E, Plante S, Boisvert M, Aoudjit F, Chakir J
   PLoS ONE, 2013;8(12):e81983.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
   Authors: Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H
   J Immunol, 2013;190(8):3939-48.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
   Authors: Badr G, Lefevre EA, Mohany M
   PLoS ONE, 2011;6(9):e23741.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells.
   Authors: Dusseaux M, Martin E, Serriari N, Peguillet I, Premel V, Louis D, Milder M, Le Bourhis L, Soudais C, Treiner E, Lantz O
   Blood, 2011;117(4):1250-9.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
   Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
   J. Immunol., 2010;184(6):2886-98.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection.
   Authors: Campillo-Gimenez L, Cumont MC, Fay M, Kared H, Monceaux V, Diop O, Muller-Trutwin M, Hurtrel B, Levy Y, Zaunders J, Dy M, Leite-de-Moraes MC, Elbim C, Estaquier J
   J. Immunol., 2010;184(2):984-92.
   Species: Primate - Macaca mulatta (Rhesus Macaque)
   Sample Type: Whole Cells
   Application: Flow


9. CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.
   Authors: Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, Kanamori A, Kannagi R, Fujimoto J, Muroi K, Furukawa Y, Nakamura M
   Cancer Res., 2008;68(3):790-9.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


10. Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
    Authors: Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, Giovarelli M
    FASEB J., 2008;22(8):2747-57.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow

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