抗Flt-4抗体(Anti-Flt-4, Mouse, Goat-Poly antibody)
掲載日情報:2019/10/21 現在Webページ番号:27257
Flt-4に対する抗体(Anti-Flt-4, Mouse, Goat-Poly )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
価格
[在庫・価格 :2025年05月01日 00時00分現在]
詳細 | 商品名 |
|
文献数 | ||
---|---|---|---|---|---|
Anti-Flt-4, Mouse, Goat-Poly <Anti-VEGF Receptor 3> |
|
75 | |||
Anti-Mouse VEGF R3/Flt-4 Affinity Purified Polyclonal Ab |
|
4 | |||
[在庫・価格 :2025年05月01日 00時00分現在]
Anti-Flt-4, Mouse, Goat-Poly <Anti-VEGF Receptor 3>
文献数: 75
- 商品コード:AF743
- メーカー:RSD
- 包装:100μg
- 価格:¥106,000
- 在庫:1個
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
Anti-Mouse VEGF R3/Flt-4 Affinity Purified Polyclonal Ab
文献数: 4
- 商品コード:AF743-SP
- メーカー:RSD
- 包装:25μg
- 価格:¥30,000
- 在庫:無(未発注)
- 納期:2~3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
追加しました。
Product Details
Species Reactivity | Mouse |
---|---|
Label | Unconjugated |
Immunogen | S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse VEGF R3/Flt-4Tyr25-Asp770Accession # P35917 |
Source | Polyclonal Goat IgG |
Purification | Antigen Affinity-purified |
Specificity | Detects mouse VEGF R3/Flt-4 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) VEGF R3, 10% cross-reactivity with rhVEGF R2, and 5% cross-reactivity with rhVEGF R1. |
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Applications and Data
Recommended Concentration | Sample | |
Western Blot | 0.1 µg/mL | Recombinant Mouse VEGF R3/Flt‑4 Fc Chimera (Catalog # 743-R3) |
Flow Cytometry | 0.25 µg/106 cells | See below |
CyTOF-ready | Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation. |
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Related Product & Information
Background | VEGF R3/Flt-4 |
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background_content | Background: VEGF R3/Flt-4 VEGF R3 (Flt-4), together with VEGF R1 (Flt-1) and VEGF R2 (KDR/Flk-1), belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of these receptors is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. In adults, VEGF R3 expression is restricted to the endothelial cells of the lymphatic vessels. Mouse VEGF R3 cDNA encodes a 1363 amino acid (aa) residue precursor protein with a 24 aa residue signal peptide. Mature VEGF R3 has a 751 aa residue extracellular domain, a 22 aa residue hydrophobic transmembrane domain and a 565 aa residue cytoplasmic domain. The polypeptide sequences of murine Flt-4 is 88% identical to the human homologue. VEGF R3 has been reported to serve as the receptors for VEGF-C and VEGF-D. |
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Citations
- Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators
Authors: CA Thomson, SA van de Pav, M Stakenborg, E Labeeuw, G Matteoli, AM Mowat, RJB Nibbs
J. Immunol., 2018;0(0):.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC - Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms
Authors: Y Zhang, MH Ulvmar, L Stanczuk, I Martinez-C, M Frye, K Alitalo, T Mäkinen
Nat Commun, 2018;9(1):1296.
Species: Mouse
Sample Type: Whole Cells
Application: ICC - Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program
Authors: M Frye, A Taddei, C Dierkes, I Martinez-C, M Fielden, H Ortsäter, J Kazenwadel, DP Calado, P Ostergaard, M Salminen, L He, NL Harvey, F Kiefer, T Mäkinen
Nat Commun, 2018;9(1):1511.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC - VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling
Authors: K Heinolaine, S Karaman, G D'Amico, T Tammela, R Sormunen, L Eklund, K Alitalo, G Zarkada
Circ. Res, 2017;0(0):.
Species: Mouse
Sample Type: Tissue Homogenates
Application: WB - Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma
Authors: J Kim, DY Park, H Bae, DY Park, D Kim, CK Lee, S Song, TY Chung, DH Lim, Y Kubota, YK Hong, Y He, HG Augustin, G Oliver, GY Koh
J. Clin. Invest., 2017;0(0):.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC - Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
Authors: SK Jha, K Rauniyar, T Karpanen, VM Leppänen, P Brouillard, M Vikkula, K Alitalo, M Jeltsch
Sci Rep, 2017;7(1):4916.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC - Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine
Authors: D Olmeda, D Cerezo-Wal, E Riveiro-Fa, PC Pennacchi, M Contreras-, N Ibarz, M Cifdaloz, X Catena, TG Calvo, E Cañón, D Alonso-Cur, J Suarez, L Osterloh, O Graña, F Mulero, D Megías, M Cañamero, JL Martínez-T, C Mondal, J Di Martino, D Lora, I Martinez-C, JJ Bravo-Cord, J Muñoz, S Puig, P Ortiz-Rome, JL Rodriguez-, S Ortega, MS Soengas
Nature, 2017;546(7660):676-680.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC paraffin embedded - Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction
Authors: F Tatin, E Renaud-Gab, AC Godet, F Hantelys, F Pujol, F Morfoisse, D Calise, F Viars, P Valet, B Masri, AC Prats, B Garmy-Susi
JCI Insight, 2017;2(12):.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC - FGF-dependent metabolic control of vascular development
Authors: P Yu, K Wilhelm, A Dubrac, JK Tung, TC Alves, JS Fang, Y Xie, J Zhu, Z Chen, F De Smet, J Zhang, SW Jin, L Sun, H Sun, RG Kibbey, KK Hirschi, N Hay, P Carmeliet, TW Chittenden, A Eichmann, M Potente, M Simons
Nature, 2017;0(0):.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC - Vitamin D inhibits lymphangiogenesis through VDR-dependent mechanisms
Authors: S Yazdani, F Poosti, L Toro, J Wedel, R Mencke, K Mirkovi?, MH de Borst, JS Alexander, G Navis, H van Goor, J van den Bo, JL Hillebrand
Sci Rep, 2017;7(0):44403.
Species: Mouse
Sample Type: Whole Cells
Application: ICC
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