抗TNF Receptor Ⅲ抗体(Anti-TNF Receptor Ⅲ, Human, Goat-Poly antibody)
掲載日情報:2019/10/21 現在Webページ番号:27171
TNF Receptor Ⅲに対する抗体(Anti-TNF Receptor Ⅲ, Human, Goat-Poly )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
価格
[在庫・価格 :2026年04月06日 18時15分現在]
| 詳細 | 商品名 |
|
文献数 | ||
|---|---|---|---|---|---|
|
Anti-TNF Receptor III, Human, Goat-Poly <Anti-Lymphotoxin β Receptor> |
|
5 | |||
|
Anti-Human Lymphotoxin beta R/TNFRSF3 Affinity Purified PAb |
|
5 | |||
[在庫・価格 :2026年04月06日 18時15分現在]
Anti-TNF Receptor III, Human, Goat-Poly <Anti-Lymphotoxin β Receptor>
文献数: 5
- 商品コード:AF629
- メーカー:RSD
- 包装:100μg
- 価格:¥83,000
- 在庫:1個
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
Anti-Human Lymphotoxin beta R/TNFRSF3 Affinity Purified PAb
文献数: 5
- 商品コード:AF629-SP
- メーカー:RSD
- 包装:25μg
- 価格:¥25,000
- 在庫:1個
- 納期:2~3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
追加しました。
Product Details
| Species Reactivity | Human |
|---|---|
| Label | Unconjugated |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Lymphotoxin beta R/TNFRSF3Ser28-Met227Accession # P36941 |
| Source | Polyclonal Goat IgG |
| Purification | Antigen Affinity-purified |
| Specificity | Detects human Lymphotoxin beta R/TNFRSF3 in direct ELISAs and Western blots. |
追加しました。
Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 0.1 µg/mL | Recombinant Human Lymphotoxin beta R/TNFRSF3 Fc Chimera (Catalog # 629-LR) |
| Flow Cytometry | 2.5 µg/106 cells | Human whole blood monocytes |
| CyTOF-ready | Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation. | |
| Inhibition of Cell Growth | When immobilized at 50 µg/mL, this antibody will inhibit HT-29 human colon adenocarcinoma cell proliferation in the presence of 10 U/mL (1 ng/mL) Recombinant Human IFN-gamma (Catalog # 285-IF) by 2-4.5 fold. | |
追加しました。
Related Product & Information
| Long Name | Lymphotoxin beta Receptor |
|---|---|
| Entrez Gene IDs | 4055 (Human); 17000 (Mouse); 297604 (Rat) |
| Background | Lymphotoxin beta R/TNFRSF3 |
| background_content | Background: Lymphotoxin beta R/TNFRSF3 Lymphotoxin beta receptor (LT beta R), also known as TNF RIII and TNF R-related protein (TNF Rrp), was originally identified as a transcribed sequence on human chromosome 12p with homology to the TNF receptor superfamily. In the new TNF nomenclature, LT beta R is referred to as TNFRSF3. Human LT beta R cDNA encodes a 435 amino acid (aa) residue type I membrane protein with a putative 30 aa residue signal peptide, a 193 aa residue extracellular domain and a 171 aa residue cytoplasmic domain. The extracellular domain of LT beta R contains four cysteine-rich motif characteristic of the TNF receptor superfamily. The cytoplasmic region of LT beta R share little sequence similarity with other TNF receptor family members, suggesting that different signaling mechanisms may be utilized. LT beta R is expressed in a variety of tissues including visceral and lymphoid tissues. LT beta R is also expressed by cell lines of monocytic, epithelial, and fibroblastic origins but not by T and B lymphocytes. The human and mouse LT beta R share 76% aa sequence homology. The TNF family ligands that have been shown to bind and activate LT beta R include LIGHT (also a ligand for HVEM) and the heterotrimeric lymphotoxin LT alpha 1/ beta 2 or LT alpha 2/ beta 1. Depending on the cell type, activation of LT beta R has been shown to induce NF kappa B activation, chemokine production, growth arrest, and apoptosis. In vivo, LT beta R has been shown to play a critical role in controlling cellular immune functions and lymphoid organogenesis. |
追加しました。
Citations
- TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
Nat Commun, 2014;5(0):3199.
Species: Human
Sample Type: Whole Cells
Application: Neut - Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence.
Authors: Takahashi A, Ohtani N, Yamakoshi K, Iida S, Tahara H, Nakayama K, Nakayama KI, Ide T, Saya H, Hara E
Nat. Cell Biol., 2006;8(11):1291-7.
Species: Human
Sample Type: Cell Lysates
Application: WB - Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses.
Authors: Girard S, Vossman E, Misek DE, Podevin P, Hanash S, Brechot C, Beretta L
Hepatology, 2004;40(3):708-18.
Species: Human
Sample Type: Cell Lysates
Application: WB - LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis.
Authors: Hikichi Y, Tsuji I, Shintani Y
J. Biol. Chem., 2002;277(51):50054-61.
Species: Human
Sample Type: Whole Cells
Application: Flow
追加しました。
製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。
