(±)14(15)-DiHET MaxSpec Standard

• 価格
• 製品情報
• 製品詳細
• 文献

価格

目次に戻る

製品情報

Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)14(15)-DiHET is the urinary metabolite of (±)14(15)-EET (Item No. 50651) which has been documented by GC-MS to be elevated in pregnancy-induced hypertension.

(±)14(15)-DiHET MaxSpec^® standard is a quantitative grade standard of (±)14(15)-DiHET (Item No. 51651) that has been prepared specifically for mass spectrometry or any application wherequantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)14(15)-DiHET MaxSpec^® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

目次に戻る

製品詳細

name	(±)14(15)-DiHET MaxSpec Standard
Formal Name	(±)14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid
Synonyms	(±)14,15-DiHETrE
Molecular Formula	C20H34O4
Formula Weight	338.5
Purity	>95%
Formulation	A solution in ethanol
SMILES	CCCCC[C@@H](O)[C@@H](O)C/C=C\C/C=C\C/C=C\CCCC(O)=O
InChI Code	InChI=1S/C20H34O4/c1-2-3-12-15-18(21)19(22)16-13-10-8-6-4-5-7-9-11-14-17-20(23)24/h4,6-7,9-10,13,18-19,21-22H,2-3,5,8,11-12,14-17H2,1H3,(H,23,24)/b6-4-,9-7-,13-10-/t18-,19+/m1/s1
InChI Key	SYAWGTIVOGUZMM-KZTFMOQPSA-N
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
Stability	≥ 1 year

目次に戻る

文献

1. Oliw, E.H., Guengerich, F.P., and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. J. Biol. Chem. 257(7), 3771-3781 (1982).

2. Catella, F., Lawson, J.A., Fitzgerald, D.J., et al. Endogenous biosynthesis of arachidonic acid epoxides in humans: Increased formation in pregnancy-induced hypertension. Proc. Natl. Acad. Sci. U.S.A. 87(15), 5893-5897 (1990).

目次に戻る