抗Anti-Human IL-17F MAb (Clone 775602R)抗体(Anti-Human IL-17F MAb (Clone 775602R antibody)
掲載日情報：2019/10/21 現在Webページ番号：232570
Anti-Human IL-17F MAb (Clone 775602R)に対する抗体(Anti-Human IL-17F MAb (Clone 775602R )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
価格
[在庫・価格 ：2025年06月01日 00時00分現在]
| 詳細 | 商品名 |
|
文献数 | ||
|---|---|---|---|---|---|
|
Anti-Human IL-17F MAb (Clone 775602R) |
|
0 | |||
|
Anti-Human IL-17F MAb (Clone 775602R) |
|
0 | |||
[在庫・価格 ：2025年06月01日 00時00分現在]
Anti-Human IL-17F MAb (Clone 775602R)
文献数： 0
- 商品コード：MAB13353-100
- メーカー：RSD
- 包装：100μg
- 価格：¥95,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
Anti-Human IL-17F MAb (Clone 775602R)
文献数： 0
- 商品コード：MAB13353-SP
- メーカー：RSD
- 包装：25μg
- 価格：¥30,000
- 在庫：無(未発注)
- 納期：2～3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
追加しました。
Product Details
| Species Reactivity | Human |
|---|---|
| Label | Unconjugated |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IL-17FGly21-Thr153Accession # Q96PD4 |
| Source | Recombinant Monoclonal Mouse IgG2B Clone # 775602R |
| Purification | Protein A or G purified from cell culture supernatant |
| Specificity | Detects human IL-17F in direct ELISAs. |
追加しました。
Applications and Data
| Recommended Concentration | Sample | |
| ELISA | This antibody functions as an ELISA detection antibody when paired with Mouse Anti-Human IL‑17F Monoclonal Antibody (Catalog # MAB13354). This product is intended for assay development on various assay platforms requiring antibody pairs. We recommend the Human IL-17F DuoSet ELISA Kit (Catalog # DY1335B-05) for convenient development of a sandwich ELISA. | |
| ELISA | |
|---|---|
 | Human IL‑17F ELISA Standard Curve. Recombinant Human IL‑17F protein was serially diluted 2-fold and captured by Mouse Anti-Human IL‑17F Monoclonal Antibody (Catalog # MAB13354) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human IL‑17F Monoclonal Antibody (Catalog # MAB13353) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994). |
追加しました。
Related Product & Information
| Background | IL-17F |
|---|---|
| background_content | Background: IL-17F The Interleukin 17 (IL‑17) family proteins, comprising six members (IL‑17A through IL‑17F), are secreted, structurally related proteins that share a conserved cystine‑knot fold near the C-terminus, but have considerable sequence divergence at the N‑terminus. With the exception of IL‑17B, which exists as a non‑covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL‑17 family proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions (1, 2).Human IL‑17F cDNA encodes a 163 aa protein with a putative 30 aa signal peptide. Among IL‑17 family members, IL‑17F is most closely related to IL-17A (approximately 44% aa sequence homology), but shares only limited sequence homology (16-30%) with IL‑17B, C, D and E. Human and mouse IL‑17F share 55% sequence identity. IL-17F is expressed in activated CD4+ T cells and activated monocytes. Five receptors (IL-17 RA, B, C, D and E) have been identified (5). Although the ligands for IL-17 RD and E are not known yet, it is reported that IL-17 RA binds IL-17A, and IL-17 RB bindsIL-17B and IL-17E. IL-17 RC binds IL-17A and IL‑17F with similarly high affinity and functions as a receptor for both IL-17A and IL-17F (5, 6). The biological activities mediated by IL‑17F are similar to those of IL‑17. IL‑17F stimulates production of IL‑6, IL‑8, G‑CSF, and regulates cartilage matrix turnover by increasing matrix release and inhibiting new matrix synthesis (4). IL‑17F also inhibits angiogenesis and induces production of IL‑2, TGF-beta, and monocyte chemoattractant protein‑1 in endothelial cells (3). |
追加しました。
製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。