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VEGF 165 Protein 組換え体(リコンビナント)タンパク質 | Recombinant Human VEGF 165 Protein

掲載日情報：2018/02/07 現在Webページ番号：215996

アールアンドディー システムス /
R&D Systems, Inc.
[メーカー略称：RSD]

R&D Systems社製の高品質なVEGF 165 Proteinの組換え体タンパク質(Recombinant Human VEGF 165 Protein)です。
※本製品は研究用です。研究用以外には使用できません。

[在庫・価格 ：2024年05月20日 08時15分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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 納期 文献数
VEGF165, Human, Recombinant <Vascular Endothelial Cell Growth Factor>
 10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。 0
説明文
純度：>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.，由来動物：Human，M.W.：19.2 kDa (monomer)，Genbank：7422，エンドトキシンレベル：<0.01 EU per 1 µg of the protein by the LAL method.，産生：Sf 21 (baculovirus)
別名：MVCD1
Genbank No： 7422
Protein Accession No： NP_001165097
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法規制等 カルタヘナ該当品
保存条件 -20℃ 法規備考
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[在庫・価格 ：2024年05月20日 08時15分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

VEGF165, Human, Recombinant <Vascular Endothelial Cell Growth Factor>

文献数： 0

説明文 純度：>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.，由来動物：Human，M.W.：19.2 kDa (monomer)，Genbank：7422，エンドトキシンレベル：<0.01 EU per 1 µg of the protein by the LAL method.，産生：Sf 21 (baculovirus)
別名：MVCD1
Genbank No： 7422
Protein Accession No： NP_001165097
別包装品 別包装品あり
法規制等 カルタヘナ該当品
保存条件 -20℃ 法規備考
掲載カタログ

製品記事
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CF(Carrier-Free)とは？

R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。

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Product Details

Source
Spodoptera frugiperda, Sf 21 (baculovirus)-derivedAla27-Arg191
Accession #
NP_001165097
Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Predicted Molecular Mass
19.2 kDa (monomer)
SDS-PAGE
20-22 kDa, reducing conditions39-42 kDa, non-reducing conditions
Activity
Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. Conn, G. et al. (1990) Proc. Natl. Acad. Sci. USA 87:1323. The ED50 for this effect is 1-6 ng/mL.The specific activity of recombinant human VEGF165 is approximately 1.7 x 103 U/μg, which is calibrated against recombinant human VEGF165 WHO Standard (NIBSC code: 02/286).

Bioactivity
Recombinant Human VEGF165 (Catalog # 293-VE) stimulates proliferation in HUVEC human umbilical vein endothelial cells. The ED50 is 1-6 ng/mL.
SDS-PAGE
1 μg/lane of Recombinant Human VEGF165 was resolved by SDS-PAGE with silver staining, under reducing (R) and non-reducing (NR) conditions, showing major bands at 20-22 kDa and 39-42 kDa, respectively. Multiple bands in gel are due to glycosylation.

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Related Product & Information

Entrez Gene IDs
7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
Background
VEGF
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult (1-3). It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues and a cystine knot structure (4). Humans express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length (4). VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189 (3, 4). Isoforms other than VEGF121 contain basic heparin-binding regions and are not freely diffusible (4). Human VEGF165 shares 88% aa sequence identity with corresponding regions of mouse and rat, 96% with porcine, 95% with canine, and 93% with feline, equine and bovine VEGF, respectively. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt-1) and VEGF R2 (Flk-1/KDR) on endothelial cells (4). Although VEGF affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity (3, 4). VEGF165 binds the semaphorin receptor, Neuropilin-1 and promotes complex formation with VEGF R2 (5). VEGF is required during embryogenesis to regulate the proliferation, migration, and survival of endothelial cells (3, 4). In adults, VEGF functions mainly in wound healing and the female reproductive cycle (3). Pathologically, it is involved in tumor angiogenesis and vascular leakage (6, 7). Circulating VEGF levels correlate with disease activity in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (8). VEGF is induced by hypoxia and cytokines such as IL-1, IL-6, IL-8, oncostatin M and TNF-alpha (3, 4, 9).

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Citations

R&D Systems personnel manually curate a database that contains references using R&D Systems products.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis
Authors: M Nagao, JL Hamilton, R Kc, AD Berendsen, X Duan, CW Cheong, X Li, HJ Im, BR Olsen
Sci Rep, 2017;7(1):13027.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
Cell Stem Cell, 2017;21(2):179-194.e4.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3
Authors: H He, AE Kuriyan, CW Su, M Mahabole, Y Zhang, YT Zhu, HW Flynn, JM Parel, SC Tseng
Sci Rep, 2017;7(0):43736.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Dual targeting of vascular endothelial growth factor and bone morphogenetic protein-9/10 impairs tumor growth through inhibition of angiogenesis
Authors: Y Akatsu, Y Yoshimatsu, T Tomizawa, K Takahashi, A Katsura, K Miyazono, T Watabe
Cancer Sci, 2017;108(1):151-155.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Gelatin device for the delivery of growth factors involved in endochondral ossification
Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
PLoS ONE, 2017;12(4):e0175095.
Species: Chicken
Sample Type: Egg
Application: Bioassay
Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis
Authors: LA Murray, DM Habiel, M Hohmann, A Camelo, H Shang, Y Zhou, AL Coelho, X Peng, M Gulati, B Crestani, MA Sleeman, T Mustelin, MW Moore, C Ryu, AD Osafo-Addo, JA Elias, CG Lee, B Hu, JD Herazo-May, DA Knight, CM Hogaboam, EL Herzog
JCI Insight, 2017;2(16):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
In smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factor
Authors: P Henno, S Grassin-De, E Belle, M Brollo, E Naline, E Sage, P Devillier, D Israël-Bie
Respir. Res., 2017;18(1):102.
Species: Human
Sample Type: Whole Tissue
Application: Bioassay
PM2.5 exposure decreases viability, migration and angiogenesis in human umbilical vein endothelial cells and human microvascular endothelial cells
Authors: S Chen, X Wu, J Hu, G Dai, A Rong, G Guo
Mol Med Rep, 2017;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
Invest. Ophthalmol. Vis. Sci., 2017;58(9):3496-3505.
Species: Bovine
Sample Type: Whole Cells
Application: Bioassay
Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A165
Authors: HL Deissler, GK Lang, GE Lang
Cell. Physiol. Biochem., 2017;42(4):1493-1513.
Species: Bovine
Sample Type: Whole Cells
Application: Bioassay
Apatinib, an Inhibitor of Vascular Endothelial Growth Factor Receptor 2, Suppresses Pathologic Ocular Neovascularization in Mice
Authors: KL Kim, W Suh
Invest. Ophthalmol. Vis. Sci., 2017;58(9):3592-3599.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis
Authors: Z Liu, S Yan, J Wang, Y Xu, Y Wang, S Zhang, X Xu, Q Yang, X Zeng, Y Zhou, X Gu, S Lu, Z Fu, DJ Fulton, NL Weintraub, RB Caldwell, W Zhang, C Wu, XL Liu, JF Chen, A Ahmad, I Kaddour-Dj, M Al-Shabraw, Q Li, X Jiang, Y Sun, A Sodhi, L Smith, M Hong, Y Huo
Nat Commun, 2017;8(1):584.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
Exp. Mol. Med., 2017;49(8):e363.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Angiogenic Effects of Collagen/Mesoporous Nanoparticle Composite Scaffold Delivering VEGF165
Biomed Res Int, 2016;2016(0):9676934.
Species: Rat
Sample Type: In Vivo
Application: In Vivo
Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response
Sci Rep, 2016;6(0):31295.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling
Sci Rep, 2016;6(0):39190.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy
Invest Ophthalmol Vis Sci, 2016;57(10):4017-26.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization
Sci Rep, 2016;6(0):26480.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
Nat Commun, 2016;7(0):13517.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Tie1 controls angiopoietin function in vascular remodeling and inflammation
J Clin Invest, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Mesenchymal Stem Cells Reshape and Provoke Proliferation of Articular Chondrocytes by Paracrine Secretion
Sci Rep, 2016;6(0):32705.
Species: Rabbit
Sample Type: Whole Cells
Application: Bioassay
Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer
Oncotarget, 2016;0(0):.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation
Authors: I Papangeli, J Kim, I Maier, S Park, A Lee, Y Kang, K Tanaka, OF Khan, H Ju, Y Kojima, K Red-Horse, DG Anderson, AF Siekmann, HJ Chun
Nat Commun, 2016;7(0):11268.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance
Authors: C Jang, SF Oh, S Wada, GC Rowe, L Liu, MC Chan, J Rhee, A Hoshino, B Kim, A Ibrahim, LG Baca, E Kim, CC Ghosh, SM Parikh, A Jiang, Q Chu, DE Forman, SH Lecker, S Krishnaiah, JD Rabinowitz, AM Weljie, JA Baur, DL Kasper, Z Arany
Nat Med, 2016;22(4):421-6.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain
Neurobiol Dis, 2016;96(0):186-200.
Species: Rat
Sample Type: In Vivo
Application: In Vivo
Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function
Authors: GJ Prud'homme, Y Glinka, Z Lichner, GM Yousef
Oncotarget, 2016;7(42):68057-68071.
Species: Human
Sample Type: RNA
Application: Bioassay
BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
Authors: Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi R, Xu W, Karakousis G, Gangadhar T, Schuchter L, Lieu M, Khare S, Halloran M, Herlyn M, Kaufman R
Clin Cancer Res, 2015;21(7):1652-64.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
Authors: Rama N, Dubrac A, Mathivet T, Ni Charthaigh R, Genet G, Cristofaro B, Pibouin-Fragner L, Ma L, Eichmann A, Chedotal A
Nat Med, 2015;21(5):483-91.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
Authors: Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G
Nat Commun, 2015;6(0):6576.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
The effect of vascular endothelial growth factor on osteoclastogenesis in rheumatoid arthritis.
Authors: Kim H, Kim K, Kim B, Cho M, Lee S
PLoS ONE, 2015;10(4):e0124909.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system.
Authors: Song B, Fan Y, He W, Zhu D, Niu X, Wang D, Ou Z, Luo M, Sun X
Stem Cells Dev, 2015;24(9):1053-65.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development.
Authors: Schaker K, Bartsch S, Patry C, Stoll S, Hillebrands J, Wieland T, Kroll J
J Biol Chem, 2015;290(10):6408-18.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
R-Ras protein inhibits autophosphorylation of vascular endothelial growth factor receptor 2 in endothelial cells and suppresses receptor activation in tumor vasculature.
Authors: Sawada J, Li F, Komatsu M
J Biol Chem, 2015;290(13):8133-45.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P).
Authors: Williams P, Stilhano R, To V, Tran L, Wong K, Silva E
PLoS ONE, 2015;10(4):e0123437.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells.
Authors: Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito M, Toyoda M, Umezawa A, Hara T
Exp Hematol, 2015;44(1):68-74.e10.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
IL-25 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma model.
Authors: Yao, Xiujuan, Wang, Wei, Li, Yan, Huang, Ping, Zhang, Qian, Wang, Jingjing, Wang, Wen, Lv, Zhe, An, Yunqing, Qin, Jianguo, Corrigan, Chris J, Huang, Kewu, Sun, Yongchan, Ying, Sun
Respir Res, 2015;16(0):39.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
JSI-124 suppresses invasion and angiogenesis of glioblastoma cells in vitro.
Authors: Yuan G, Yan S, Xue H, Zhang P, Sun J, Li G
PLoS ONE, 2015;10(3):e0118894.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Ecto-5'-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature.
Authors: Yegutkin G, Auvinen K, Rantakari P, Hollmen M, Karikoski M, Grenman R, Elima K, Jalkanen S, Salmi M
Eur J Immunol, 2015;45(2):562-73.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Inhibition of IGF-1-Mediated Cellular Migration and Invasion by Migracin A in Ovarian Clear Cell Carcinoma Cells.
Authors: Ukaji T, Lin Y, Banno K, Okada S, Umezawa K
PLoS ONE, 2015;10(9):e0137663.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2.
Authors: Zhao D, Pan C, Sun J, Gilbert C, Drews-Elger K, Azzam D, Picon-Ruiz M, Kim M, Ullmer W, El-Ashry D, Creighton C, Slingerland J
Oncogene, 2015;34(24):3107-19.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
The proangiogenic effect of iroquois homeobox transcription factor Irx3 in human microvascular endothelial cells.
Authors: Scarlett K, Pattabiraman V, Barnett P, Liu D, Anderson L
J Biol Chem, 2015;290(10):6303-15.
Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity.
Authors: Teran M, Nugent M
J Biol Chem, 2015;290(26):16451-62.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Insulin-like growth factor 1 (IGF-1) stabilizes nascent blood vessels.
Authors: Jacobo S, Kazlauskas A
J Biol Chem, 2015;290(10):6349-60.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
Authors: Adini, Irit, Ghosh, Kaustabh, Adini, Avner, Chi, Zai-Long, Yoshimura, Takeru, Benny, Ofra, Connor, Kip M, Rogers, Michael, Bazinet, Lauren, Birsner, Amy E, Bielenberg, Diane R, D'Amato, Robert J
J Clin Invest, 2014;124(1):425-36.
Species: Human
Sample Type: Whole Cells
Application: cell culture
Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity.
Authors: Fleetwood F, Klint S, Hanze M, Gunneriusson E, Frejd F, Stahl S, Lofblom J
Sci Rep, 2014;4(0):7518.
Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
Authors: Cubbon R, Yuldasheva N, Viswambharan H, Mercer B, Baliga V, Stephen S, Askham J, Sukumar P, Skromna A, Mughal R, Walker A, Bruns A, Bailey M, Galloway S, Imrie H, Gage M, Rakobowchuk M, Li J, Porter K, Ponnambalam S, Wheatcroft S, Beech D, Kearney M
Stem Cells, 2014;32(10):2714-23.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Conformational remodeling of the fibronectin matrix selectively regulates VEGF signaling.
Authors: Ambesi A, McKeown-Longo P
J Cell Sci, 2014;127(0):3805-16.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Angiogenic sprouting is regulated by endothelial cell expression of Slug.
Authors: Welch-Reardon K, Ehsan S, Wang K, Wu N, Newman A, Romero-Lopez M, Fong A, George S, Edwards R, Hughes C
J Cell Sci, 2014;127(0):2017-28.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Effects of sFlt-1 and alpha 2-macroglobulin on vascular endothelial growth factor-induced endothelin-1 upregulation in human microvascular endothelial cells.
Authors: Yi K, Jung S, Cho G, Seol H, Hong S, Oh M, Kim H
Placenta, 2014;35(1):64-9.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment.
Authors: Sharghi-Namini S, Tan E, Ong L, Ge R, Asada H
Sci Rep, 2014;4(0):4031.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
Authors: Fan J, Ponferrada V, Sato T, Vemaraju S, Fruttiger M, Gerhardt H, Ferrara N, Lang R
Development, 2014;141(2):448-59.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.
Authors: Falcon B, Swearingen M, Gough W, Lee L, Foreman R, Uhlik M, Hanson J, Lee J, McClure D, Chintharlapalli S
PLoS ONE, 2014;9(9):e106901.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Peroxisome proliferator-activated receptor gamma ligands inhibit VEGF-mediated vasculogenic mimicry of prostate cancer through the AKT signaling pathway.
Authors: Qin L, Ren Y, Chen A, Guo F, Xu F, Gong C, Cheng P, Du Y, Liao H
Mol Med Rep, 2014;10(1):276-82.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development.
Authors: Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y
PLoS ONE, 2014;9(4):e94239.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling.
Authors: Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, Moser C, Shaleh H, Thornburgh S, Walters I, Roberts L
PLoS ONE, 2014;9(4):e92273.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
Authors: Seano G, Chiaverina G, Gagliardi P, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain R, Serini G, Bussolino F, Primo L
Nat Cell Biol, 2014;16(10):931-41, 1-8.
Species: Human
Sample Type: Whole Cells
Application: cell culture
Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.
Authors: Orlova, Valeria, Drabsch, Yvette, Freund, Christia, Petrus-Reurer, Sandra, van den Hil, Francijn, Muenthaisong, Suchitra, Dijke, Peter Te, Mummery, Christin
Arterioscler Thromb Vasc Biol, 2014;34(1):177-86.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase Cys-674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery.
Authors: Thompson M, Mei Y, Weisbrod R, Silver M, Shukla P, Bolotina V, Cohen R, Tong X
J Biol Chem, 2014;289(29):19907-16.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.
Authors: Orlova, Valeria, van den Hil, Francijn, Petrus-Reurer, Sandra, Drabsch, Yvette, Ten Dijke, Peter, Mummery, Christin
Nat Protoc, 2014;9(6):1514-31.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.
Authors: Morishima, Tatsuya, Watanabe, Ken-ichi, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsu, Hiramatsu, Hidefumi, Saito, Megumu K, Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutos, Heike, Toshio
Haematologica, 2014;99(1):19-27.
Species: Human
Sample Type: Whole Cells
Application: Bioassay

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製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。